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Table 3 Demographic, clinical and laboratory parameters in secondary glomerulopathies

From: The spectrum of biopsy-proven glomerular diseases in a tertiary Hospital in Southern Brazil

 

LN

DKD

SV

S-FSGS

S-MPGN

TMA

A-MM-LCDD

Others

P value

Age (years; %)

        

< 0.0011

 18-35

58.9

10.6

18.5

18.9

24

45

10

26.5

 

 36-50

26.5

21.3

18.5

37.7

24

40

13.3

17.6

 

 51-65

11.9

57.4

33.3

34

48

5

40

44.1

 

  > 65

2.7

10.6

29.6

9.4

4

10

36.7

11.8

 

Sex (%)

        

< 0.001

 Female

85.4

43.6

51.9

43.4

36

75

60

32.4

 

 Male

14.6

56.4

48.1

56.6

64

25

40

67.6

 

Ethnicity (%)

        

0.007

 Caucasian

84

76.6

94.4

75.5

84

95

76.7

70.6

 

 Afro-descendant

16

23.4

5.6

22.6

12

5

23.3

29.4

 

 Amerindian

0

0

0

1,9

4

0

0

0

 

DM (%)

8.9

100

22.9

28.6

15.8

9.1

5.9

25

< 0.001

SAH (%)

71.4

95.4

80.6

90.5

78.9

81.8

94.1

96

< 0.001

Weight

68 ± 16

78 ± 17

74 ± 18

72 ± 15

73 ± 19

87 ± 31

64 ± 13

81 ± 14

0.0072

Serum creatinine

0.8(0.6-1.1)

2.8 (1.4-4.5)

3.1(2.2-5.5)

2.0 (1.2-3.5)

1.8 (1.4-3.2)

4.1(3.1-6.6)

2.9 (0.9-4.9)

1.5 (1.0-2.3)

< 0.0013

eGFR

98 (62-120)

22 (13-50)

19 (9.9-25)

32 (16-53)

37 (18-48)

13 (8.3-17)

21 (11-69)

47 (24-82)

< 0.001

Proteinuria

2.1(0,7-4.2)

6.0 (3.7-9,2)

1.5 (0.9-3.2)

2.5 (1.5-6.5)

5.0 (2.9-6.7)

1.9 (1.4-3.0)

4.8 (2.5-8.6)

3.5 (1.1-6.2)

< 0.001

Serum albumin

3.0 ± 0.7

2.8 ± 0.6

3.2 ± 0.6

3.2 ± 1.0

2.5 ± 0.8

3.2 ± 0.6

2.9 ± 1.0

2.9 ± 0.8

0.009

Total Cholesterol

229 (176-284)

197 (158-239)

217 (150-255)

208 (172-288)

199 (123-284)

171 (157-227)

220 (181-261)

242 (186-287)

0.081

Triglycerides

170 (114-255)

170 (121-270)

159 (108-165)

250 (172-418)

170 (129-257)

219 (116-375)

170 (127-203)

127 (107-274)

0.011

C3a

72 ± 33

125 ± 33

121 ± 31

120 ± 40

92 ± 41

110 ± 34

119 ± 31

108 ± 47

< 0.001

C4b

12 ± 11

35 ± 13

29 ± 13

30 ± 13

21 ± 12

30 ± 11

41 ± 20

27 ± 18

< 0.001

Anti-HIV (N,%)c

2 (1.2)

11 (12.4)

0

30(58.8)

6 (24)

1 (6.7)

0

8(24.2)

< 0.001

Anti-HCV (N,%)d

3 (1.7)

26 (29.5)

4 (7.8)

9 (18)

18 (75)

2 (11.8)

1 (3.7)

10 (30.3)

< 0.001

HbsAg (N,%)e

1 (0.6)

1 (1.2)

0

6 (12)

5 (20)

0

2 (7.4)

0

< 0.001

  1. DM diabetes mellitus, SAH systemic arterial hypertension, eGFR estimated glomerular filtration rate), LN lupus nephritis, DKD diabetic kidney disease, SV systemic vasculitis, S-FSGS secondary focal segmental glomerulosclerosis, S-MPGN secondary membranoproliferative glomerulonephritis, TMA: thrombotic microangiopathy, A-M-LCDD amyloidosis, multiple myeloma, light chain deposition disease; Other diagnoses: other secondary glomerulopathies
  2. 1N(%): Chi-square test
  3. 2Mean ± standard deviation: ANOVA
  4. 3Median (interquartile range): Kruskal-Wallis test
  5. Number of patients with measured serological parameters: aC3: 455; bC4: 455; canti-HIV: 461; danti-HCV: 465; eHbsAg: 461
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BMC Nephrology

ISSN: 1471-2369

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