Table 3 Performance of renal arrest biomarkers for predicting septic AKI progression or AKI progression with death in single or combination with renal damage biomarkers
From: Combining renal cell arrest and damage biomarkers to predict progressive AKI in patient with sepsis
Outcomes | AUC | 95% CI |
|---|---|---|
AKI progression | ||
 u[TIMP-2]*[IGFBP7] | 0.745 | 0.667 to 0.823 |
 u[TIMP-2]*[IGFBP7] + uKIM-1 | 0.752 | 0.675 to 0.828 |
 u[TIMP-2]*[IGFBP7] + uIL-18 | 0.747 | 0.669 to 0.825 |
 u[TIMP-2]*[IGFBP7] + uACR | 0.745 | 0.668 to 0.823 |
 u[TIMP-2]*[IGFBP7] + uKIM-1 + uIL-18 + uACR | 0.755 | 0.679 to 0.832 |
AKI progression with death | ||
 u[TIMP-2]*[IGFBP7] | 0.777 | 0.700 to 0.854 |
 u[TIMP-2]*[IGFBP7] + uKIM-1 | 0.782 | 0.705 to 0.859 |
 u[TIMP-2]*[IGFBP7] + uIL-18 | 0.777 | 0.700 to 0.854 |
 u[TIMP-2]*[IGFBP7] + uACR | 0.778 | 0.700 to 0.855 |
 u[TIMP-2]*[IGFBP7] + uKIM-1 + uIL-18 + uACR | 0.780 | 0.703 to 0.857 |