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Table 1 Clinical characteristics and laboratory parameters of older patients with or without CKD

From: Decreased B lymphocytes subpopulations are associated with higher atherosclerotic risk in elderly patients with moderate-to-severe chronic kidney diseases

 

Control subjects

CKD patients

P value

Number of cases

76

143

 

Age, years

80.32 ± 4.34

82.70 ± 4.89

< 0.001*

Gender (M/F)

60/16

115/28

< 0.001*

Hypertension

60.53%

86.01%

< 0.001*

Systolic blood pressure, mmHg

134.37 ± 16.78

143.66 ± 16.62

< 0.001*

Diastolic blood pressure, mmHg

71.17 ± 9.09

74.66 ± 10.22

0.005*

Diabetes

23.68%

42.66%

0.005*

SCr (μmol/L)

77.64 ± 11.47

145.55 ± 50.42

< 0.001*

eGFR CKD − EPI (ml/min/1.73 m2)

78.32 ± 10.65

40.98 ± 13.49

< 0.001*

Albumin (g/L)

35.00 ± 33.72

33.72 ± 4.97

0.075

protein/creatinine ratio (mg/g Cr)

115.17 ± 98.40

776.87 ± 1587.69

< 0.001*

Cholesterol (mmol/L)

4.19 ± 0.90

4.43 ± 1.29

0.401

Triglyceride (mmol/L)

1.12 ± 0.60

1.36 ± 0.89

0.040*

IMT (cm)

0.94 ± 0.16

1.01 ± 0.17

0.006*

WBC (109 /L)

6.17 ± 1.95

6.43 ± 1.92

0.247

Neutrophil (109 /L)

3.75 ± 1.51

4.20 ± 1.59

0.027*

T lymphocytes (109 /L)

1.09 ± 0.44

0.33 ± 0.21

0.175

Total CD19(+) B lymphocytes (109 /L)

0.22 ± 0.36

0.15 ± 0.11

0.059

CD19(+)CD5(+) B lymphocytes (109 /L)

0.10 ± 0.33

0.05 ± 0.07

0.040*

CD19(+)CD5(−) B lymphocytes (109 /L)

0.12 ± 0.09

0.10 ± 0.06

0.088

Number of deaths

9

46

0.001*

Follow up time

50.37 ± 31.59

38.46 ± 29.56

0.009*

  1. eGFR Estimated glomerular filtration rate, SCr Serum creatinine, IMT Intima–media thickness, WBC White blood cell