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Table 3 The association of childhood HLS as continuous and categorical variables with SKD, UACR, and eGFR in midlife (2014–19)

From: Associations of a healthy lifestyle score from childhood to adulthood with subclinical kidney damage in midlife: a population-based cohort study

  

SKD RR (95% CI)

UACR (mg/mmol)

eGFR (ml/min/1.73m2)

  

RR (95% CI)

β 95% CI

β 95% CI

 

SKD/n (%)

Unadjusted

Adjusted a

Unadjusted

Adjusted a

Unadjusted

Adjusted a

Childhood HLS

–

1.01 (0.82 to 1.25)

1.04 (0.84 to 1.30)

−0.01 (− 0.03 to 0.01)

−0.01 (− 0.02 to 0.01)

0.04 (− 0.53 to 0.60)

−0.06 (− 0.62 to 0.49)

Childhood HLS category b

  Healthy

27/580 (4.7)

1.00

1.00

1.00

1.00

1.00

1.00

  Unhealthy

9/160 (5.6)

1.21 (0.58 to 2.52)

1.07 (0.49 to 2.30)

0.09 (0.01 to 0.18)

0.06 (−0.01 to 0.13)

0.26 (−1.85 to 2.36)

0.68 (−1.41 to 2.78)

  1. HLS healthy lifestyle score; SKD subclinical kidney damage; UACR urinary albumin-creatinine ratio; eGFR estimated glomerular filtration rate; RRrelative risk; CI confidence interval
  2. a adjusted for childhood age, sex, socio-economic position in childhood, education, occupation in midlife, and the duration of follow-up
  3. b childhood HLS category was defined as unhealthy with HLS range from 0 to 5, and healthy with HLS range from 6 to 10