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Table 2 Correlations between Hcy and clinicopathologic parameters in IgAN patients

From: Serum homocysteine is associated with tubular interstitial lesions at the early stage of IgA nephropathy

Variable

r

P

Age

0.18

0.001*

MAP

0.24

< 0.001**

Scr

0.69

< 0.001**

eGFR

−0.62

< 0.001**

BUN

0.57

< 0.001**

UA

0.42

< 0.001**

24-h urine protein

0.22

< 0.001**

Hb

−0.15

0.008*

ALB

0.05

0.338

Glu

0.02

0.695

CHOL

−0.02

0.718

TG

0.21

< 0.001**

LDL

0.01

0.834

HDL

−0.31

< 0.001**

SOD

−0.23

< 0.001**

hsCRP

0.22

< 0.001**

ESR

0.13

0.016*

IgA

0.04

0.435

IgM

−0.16

0.004*

IgG

0.07

0.214

C3

0.03

0.533

C4

0.14

0.010*

M

0.01

0.869

E

0.12

0.026*

S

0.04

0.500

T

0.45

< 0.001**

C

−0.01

0.822

  1. Abbreviations: MAP mean arterial pressure, Scr serum creatinine, eGFR estimated glomerular filtration rate, BUN blood urine nitrogen, UA uric acid, Hb hemoglobin, ALB serum albumin, Glu fasting glucose, CHOL cholesterol, TG triglyceride, LDL low-density lipoprotein-cholesterol, HDL high-density lipoprotein-cholesterol, SOD superoxide dismutase, hsCRP high sensitivity C reaction protein, ESR erythrocyte sedimentatio rate, IgA immunoglobulin A, IgM immunoglobulin M, IgG immunoglobulin G, C3 complement3, C4 complement4, M mesangial hypercellularity, E endocapillary hypercellularity, S segmental glomerulosclerosis, T tubular atrophy and interstitial fibrosis, C crescents
  2. *P < 0.05, **P < 0.001