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Table 3 Maternal and fetal outcomes in pregnant women with LN.

From: Fetal and maternal outcome in patients with active lupus nephritis: comparison between new-onset and pre-existing lupus nephritis

 

Total (n = 73)

Pre-existing LN (n = 38)

New-onset LN (n = 35)

P value

Fetal outcomes

    

Gestational age, weeks*

24.0 (14.0, 34.1)

29.8 (16.5, 35.4)

20.3 (9.0, 30.4)

0.02

Live-born infant's age, weeks

35.0 (31.4,36.6)

35.2 (33.0,36.5)

32.1 (30.4,37.0)

0.13

Preterm delivery (%)#

24/36 (66.7)

17/21 (81.0)

7/15 (46.7)

0.02

Live-born infant's weight, kg

2.0 (1.4, 2.6)

2.1 (1.5,2.7)

1.6 (1.3,2.5)

0.27

Low birth weight (%)#

18/36 (50.0)

11/21 (52.4)

7/15 (46.7)

0.38

Fetal distress (%)

6 (8.2)

5 (13.2)

1 (2.9)

0.20

Fetal loss (%)

37 (50.7)

17 (44.7)

20 (57.1)

0.23

Composite fetal outcomes (%)

65 (89.0)

37 (97.4)

28 (80.0)

0.018

Maternal outcomes, n (%)

    

Cesarean section (%)

33 (45.2)

21 (55.3)

12 (34.3)

0.032

Preeclampsia

14 (19.2)

10 (26.3)

4 (11.4)

0.14

Composite maternal outcomes

37 (50.7)

23 (60.5)

14 (40.0)

0.10

  1. Data are presented as median (range) or as number (percentage). The p-values of categorical variable obtained with the Chi square or Fisher's exact test and continuous variables obtained with the Mann Whitney U-test.
  2. LN lupus nephritis
  3. *Including the live-born infant and fetal loss.
  4. #Both denominator are the total number of live-born infant.