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Table 3 Maternal and fetal outcomes in pregnant women with LN.

From: Fetal and maternal outcome in patients with active lupus nephritis: comparison between new-onset and pre-existing lupus nephritis

  Total (n = 73) Pre-existing LN (n = 38) New-onset LN (n = 35) P value
Fetal outcomes     
Gestational age, weeks* 24.0 (14.0, 34.1) 29.8 (16.5, 35.4) 20.3 (9.0, 30.4) 0.02
Live-born infant's age, weeks 35.0 (31.4,36.6) 35.2 (33.0,36.5) 32.1 (30.4,37.0) 0.13
Preterm delivery (%)# 24/36 (66.7) 17/21 (81.0) 7/15 (46.7) 0.02
Live-born infant's weight, kg 2.0 (1.4, 2.6) 2.1 (1.5,2.7) 1.6 (1.3,2.5) 0.27
Low birth weight (%)# 18/36 (50.0) 11/21 (52.4) 7/15 (46.7) 0.38
Fetal distress (%) 6 (8.2) 5 (13.2) 1 (2.9) 0.20
Fetal loss (%) 37 (50.7) 17 (44.7) 20 (57.1) 0.23
Composite fetal outcomes (%) 65 (89.0) 37 (97.4) 28 (80.0) 0.018
Maternal outcomes, n (%)     
Cesarean section (%) 33 (45.2) 21 (55.3) 12 (34.3) 0.032
Preeclampsia 14 (19.2) 10 (26.3) 4 (11.4) 0.14
Composite maternal outcomes 37 (50.7) 23 (60.5) 14 (40.0) 0.10
  1. Data are presented as median (range) or as number (percentage). The p-values of categorical variable obtained with the Chi square or Fisher's exact test and continuous variables obtained with the Mann Whitney U-test.
  2. LN lupus nephritis
  3. *Including the live-born infant and fetal loss.
  4. #Both denominator are the total number of live-born infant.