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Table 3 Univariate and multivariable Cox regression analysis of prognostic factors for all–cause mortality

From: Serum Galectin-3 levels and all-cause and cardiovascular mortality in maintenance hemodialysis patients: a prospective cohort study

Characteristic

Cox Univariate

Cox Multivariate

HR (95% CI)

P–value

HR (95% CI)

P–value

HR (95% CI)

P–value

Galectin–3 (> 8.65 versus ≤8.65 ng/ml)

1.92 (1.17–3.17)

0.01

1.59 (0.96–2.65)

0.07

Galectin–3 (continuous variable)

0.99 (0.97–1.02)

0.70

0.99 (0.96–1.03)

0.74

Age (years)

1.07 (1.05–1.08)

P < 0.01

1.06 (1.04–1.07)

P < 0.01

1.06 (1.04–1.08)

P < 0.01

ESRD due to diabetes (yes versus no)

2.67 (2.00–3.57)

P < 0.01

2.20 (1.34–3.59)

P < 0.01

2.12 (1.30–3.46)

P < 0.01

ESRD due to glomerulonephritis (yes versus no)

0.33 (0.23–0.47)

P < 0.01

    

ESRD due to hypertension (yes versus no)

1.50 (1.08–2.10)

0.02

    

Hemoglobin (g/l)

0.99 (0.98–1.00)

0.02

    

Albumin (g/l)

0.85 (0.81–0.89)

P < 0.01

0.93 (0.88–0.99)

0.01

0.93 (0.88–0.98)

0.01

Dialysis dose (spKt/V)

0.45 (0.24–0.85)

0.01

0.38 (0.19–0.77)

P < 0.01

0.37 (0.18–0.75)

P < 0.01

Alkaline phosphatase (u/l)

1.003 (1.001–1.004)

P < 0.01

1.004 (1.002–1.005)

P < 0.01

1.004 (1.002–1.005)

P < 0.01

Sodium (mmol/l)

0.93 (0.89–0.97)

P < 0.01

    
  1. Abbreviations: CI confidence interval, ESRD end–stage renal disease, HR hazard ratio