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Table 4 Univariate and multivariable Cox regression analysis of prognostic factors for cardiovascular mortality

From: Serum Galectin-3 levels and all-cause and cardiovascular mortality in maintenance hemodialysis patients: a prospective cohort study

Characteristic

Cox Univariate

Cox Multivariate

HR (95% CI)

P–value

HR (95% CI)

P–value

HR (95% CI)

P–value

Galectin–3 (> 8.65 versus ≤8.65 ng/ml)

2.47 (1.25–4.87)

P < 0.01

2.13 (1.07–4.26)

0.03

Galectin–3 (continuous variable)

1.01 (0.97–1.05)

0.61

1.01 (0.98–1.05)

0.49

Age (years)

1.06 (1.05–1.08)

P < 0.01

1.05 (1.03–1.07)

P < 0.01

1.05 (1.04–1.07)

P < 0.01

ESRD due to diabetes (yes versus no)

2.66 (1.86–3.80)

P < 0.01

2.52 (1.35–4.72)

P < 0.01

2.43 (1.30–4.53)

P < 0.01

ESRD due to glomerulonephritis (yes versus no)

0.35 (0.23–0.54)

P < 0.01

    

ESRD due to hypertension (yes versus no)

1.53 (1.02–2.30)

0.04

2.01 (1.04–3.88)

0.04

  

Albumin (g/l)

0.85 (0.80–0.90)

P < 0.01

0.91 (0.85–0.97)

P < 0.01

0.91 (0.85–0.97)

P < 0.01

Single–pool Kt/V

0.38 (0.18–0.83)

0.01

0.30 (0.12–0.72)

P < 0.01

0.29 (0.12–0.69)

P < 0.01

Alkaline phosphatase (u/l)

1.003 (1.001–1.004)

0.001

1.004 (1.002–1.005)

P < 0.01

1.004 (1.002–1.005)

P < 0.01

Sodium (mmol/l)

0.92 (0.88–0.97)

P < 0.01

    
  1. Abbreviations: CI confidence interval, ESRD end–stage renal disease, HR hazard ratio