Table 2 The AUC, p value, cut-off value, sensitivity and specificity of studied genes
From: The effect of BKV reactivation on cytokines behavior in kidney transplanted patients
Gene Name | AUC (95% CI) | p Value | Cut Off Value | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|---|
IL-27 | 0.956 (0.872–0.991) | ≤0.001 | ≤6.5 | 93.55 (78.6–99.2) | 93.75 (79.2–99.2) |
IL-27R (WSX-1) | 0.652 (0.522–0.868) | 0.051 | ≤3.84 | 74.19 (55.4–88.1) | 71.87 (53.3–86.3) |
IFN-γ | 0.827 (0.711–0.911) | ≤0.001 | ≤9.65 | 93.55 (78.6–99.2) | 68.75 (50–83.9) |
TNF-α | 0.757 (0.632–0.856) | ≤0.0001 | ≤36.76 | 96.5 (78.6–99.2) | 68.75 (50–83.9) |
TNFR1 | 0.578 (0.447–0.701) | 0.299 | > 3.92 | 93.55 (78.6–99.2) | 34.38 (18.6–53.2) |
TNFR2 | 0.846 (0.733–0.924) | ≤0.0001 | ≤3.46 | 96.77 (83.3–99.9) | 65.62 (46.8–81.4) |
IRF3 | 0.702 (0.574–0.811) | 0.002 | > 0.44 | 51.61(33.1–69.8) | 84.37 (67.2–94.7) |
IRF7 | 0.982 (0.911–0.999) | ≤0.0001 | ≤2.13 | 90.32 (74.2–98.0) | 96.87 (83.8–99.9) |
TLR3 | 0.621 (0.490–0.741) | 0.108 | ≤1.36 | 70.97 (52.0–85.8) | 65.62 (46.8–81.4) |
TLR4 | 0.559 (0.428–0.684) | 0.427 | ≤0.14 | 48.39 (30.2–66.9) | 68.75 (50.0–83.9) |