Xanthine oxidoreductase activity in platelet-poor and rich plasma as a oxidative stress indicator in patients required renal replacement therapy

Table 8 The influence of particular parameters on the activity of xanthine oxidoreductase isoforms

Parameters	XD in PPP	XDO in PPP	XO in PPP	XD in PRP	XDO in PRP	XO in PRP
Gender	NS	NS	NS	NS	0,03	NS
Renal replacement therapy and duration of dialysis	0,002	0,004	<0,001	<0,001	0,012	<0,001
Renal replacement therapy and age	<0,001	<0,001	<0,001	<0,001	<0,001	<0,001
Stage of CKD	<0,001	0,018	NS	NS	NS	0,03
Causes of CKD	0,021	NS	NS	0,01	NS	NS

The table presents p values defining statistical significance. The relationship between gender, duration of dialysis, age, stage of chronic kidney disease and the causes of chronic kidney disease and the activity of XOR isoforms was assessed using one-way ANOVA
HD and duration of dialysis - the relationship between the type of therapy (hemodialysis, peritoneal dialysis, patients before kidney transplantation), duration of dialysis and the activity of XOR isoforms
HD and age - dependence between the studied groups (hemodialysis, peritoneal dialysis, conservative treatment, patients before kidney transplantation and control group), patients’ age and XOR isoform activity
The stage of chronic kidney disease - the relationship between the severity of chronic kidney disease based on eGFR and the activity of XOR isoforms
The causes of chronic kidney disease - the relationship between selected causes of chronic disease and the activity of XOR isoforms
NS no statistically significant relationship was found

ISSN: 1471-2369