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Table 3 Characteristics of patients at 3-months after OLT between the training set and validation set

From: Prediction of chronic kidney disease after orthotopic liver transplantation: development and validation of a nomogram model

Characteristic

Training set

(n = 293)

Validation set

(n = 106)

p-value

Neutrophils (× 109/L)

2.49 (1.86-3.50)

2.61 (1.92-3.57)

0.43

Lymphocyte (×  109/L)

1.15 (0.88-1.54)

1.16 (0.8-1.57)

0.70

Hemoglobin (g/L)

130 (117-139)

130 (119-141)

0.64

Platelet (× 109/L)

114 (90-175)

132 (93-186)

0.11

NLR

2.17 (1.49-3.06)

2.33 (1.58-3.50)

0.22

PLR

102.99 (76.47-151.76)

120.41 (87.33-161.27)

0.04

N/LP

0.018 (0.012-0.027)

0.018 (0.01-0.029)

0.92

Albumin (g/L)

41.60 (37.41-44.70)

42.80 (39.50-45.42)

0.02

TBIL (μmol/L)

15.26 (11.33-19.49)

15.30 (11.08-21.25)

0.88

DBIL (μmol/L)

5.22 (4.14-7.40)

5.48 (3.80-7.79)

0.89

ALT (U/L)

21.00 (15.00-37.00)

22.00 (14.00-36.00)

0.95

AST (U/L)

20.00 (16.00-27.00)

20.00 (16.00-30.00)

0.34

Glu (mmol/L)

5.47 (4.79-6.28)

5.37 (4.86-6.35)

0.87

CysC (mg/L)

1.135 (0.965-1.375)

1.125 (0.985-1.325)

0.99

C1q (mg/L)

168 (139-198)

171 (145-194)

0.74

BUN (mmol/L)

5.90 (4.91-7.58)

5.97 (4.94-6.97)

0.70

sCr (μmol/L)

85.00 (66.00-93.00)

80.00 (60.00-93.00)

0.19

UA (μmol/L)

359.00 (305.00-439.00)

356.00 (292.00-416.00)

0.38

eGFR (mL/min/1.73 m2)

92.76 (80.28-131.31)

99.72 (80.29-147.29)

0.24

Average concentration of FK506

7.00 (5.40-8.50)

7.35 (5.15-8.98)

0.51

Average concentration of CsA

390.60 (246.25-575.35)

121.28 (73.68-478.19)

0.09

Average concentration of Rapamycin

4.14 (3.59-5.12)

3.97 (2.92-4.51)

0.33

  1. Continuous variables are displayed as median and interquartile ranges
  2. Abbreviations: NLR Neutrophil lymphocyte ratio, PLR Platelet lymphocyte ratio, N/LP Ratio of Neutrophil to lymphocyte and platelet, TBIL Serum total bilirubin, DBIL Serum direct bilirubin, IBIL Serum indirect bilirubin, ALT Alanine aminotransferase, AST Aspartate aminotransferase, LDH Lactate dehydrogenase, Glu Glucose, CysC Cystatin, C1q Complement C1q, BUN Blood urea nitrogen, sCr Serum creatinine, UA Uric acid, eGFR Estimated glomerular filtration rate, FK506 Tacrolimus, CsA Cyclosporin A