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Fig. 1 | BMC Nephrology

Fig. 1

From: CUBN gene mutations may cause focal segmental glomerulosclerosis (FSGS) in children

Fig. 1

The renal pathologies of three patients. Kidney pathologies of three patients under light microscope are showing in Fig. 1 A-D. All of them have focal segmental glomerulosclerosis, mild mesangial cell proliferation, and interstitial fibrosis. (A) shows focal segmental glomerular sclerosis (pointed by red arrow) from patient 1. (B) and (C) show crescents in renal pathologies respectively from patient 1 and patient 2. (D) shows interstitial fibrosis (pointed by red arrow) from patient 1. podocyte pathologies of three patients under electron microscopy are showing in Fig. 1 E-F. All of them have effacement of foot processes and podocyte microvillation. (E) shows podocyte microvillation (pointed by red arrow) from patient 1. (F) shows effacement of foot processes (pointed by red arrow) from patient 2

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