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Table 2 Changes of urine protein, serum creatinine, and eGFR over time

From: The effectiveness and safety of corticosteroid therapy for IgA nephropathy with crescents: a prospective, randomized, controlled study

Variables

1–2-3 (n = 34)

1–3-5 (n = 34)

All (n = 68)

P

Urine protein, g/24 h

 Month 1

2.04 ± 1.81

1.74 ± 0.93

1.89 ± 1.43

0.392

 Month 2

1.35 ± 1.53

1.35 ± 0.88

1.35 ± 1.24

0.985

 Month 3

0.97 ± 1.40

0.99 ± 0.83

0.98 ± 1.14

0.953

 Month 4

0.85 ± 1.25

0.91 ± 0.79

0.88 ± 1.04

0.816

 Month 5

0.88 ± 1.18

0.75 ± 0.74

0.82 ± 0.98

0.589

 Month 6

0.64 ± 1.09

0.73 ± 0.79

0.68 ± 0.95

0.703

 P among time-points

< 0.001

< 0.001

< 0.001

 

Serum creatinine, μmol/L

 Month 1

98.39 ± 38.20

105.51 ± 47.16

101.95 ± 42.74

0.496

 Month 2

94.31 ± 32.77

100.54 ± 40.69

97.43 ± 36.80

0.489

 Month 3

91.18 ± 31.50

101.99 ± 39.44

96.59 ± 35.84

0.216

 Month 4

91.19 ± 31.83

101.06 ± 39.48

96.13 ± 35.94

0.260

 Month 5

87.83 ± 27.92

94.86 ± 34.09

91.34 ± 31.13

0.356

 Month 6

85.79 ± 27.60

96.27 ± 32.00

91.03 ± 30.12

0.153

 P among time-points

< 0.001

0.013

< 0.001

 

eGFR, ml/min/1.73m2

 Month 1

89.86 ± 39.47

79.92 ± 31.23

84.89 ± 35.67

0.254

 Month 2

93.02 ± 41.86

87.10 ± 46.13

90.06 ± 43.82

0.581

 Month 3

94.73 ± 36.61

84.03 ± 40.92

89.38 ± 38.91

0.260

 Month 4

95.62 ± 39.31

85.44 ± 41.45

90.53 ± 40.42

0.302

 Month 5

97.95 ± 38.37

90.28 ± 38.94

94.12 ± 38.56

0.416

 Month 6

100.41 ± 37.28

87.90 ± 44.56

94.16 ± 41.26

0.214

 P among time-points

0.010

0.045

0.001