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Table 2 Relative risk of all-cause mortality in patients with chronic kidney disease in trials of ≥12 months follow-up in which left ventricular mass was reduced in the intervention group relative to the control group and there was ≥1 event in ≥1 group

From: Left ventricular mass regression, all-cause and cardiovascular mortality in chronic kidney disease: a meta-analysis

Author, Year

N

RR

95% CI

% Weight

Lower

Upper

Schrier, 2002 [33]

79

0.881

0.057

13.594

0.70

Levin, 2005 [37]

172

0.341

0.036

3.216

1.05

Parfrey, 2005 [38]

596

0.659

0.334

1.300

11.39

Yu, 2006 [40]

46

2.760

0.118

64.415

0.53

Macdougall, 2007 [43]

197

0.338

0.042

2.753

1.20

Cianciaruso, 2008 [45]

95

3.191

0.133

76.419

0.52

Pappas, 2008 [46]

31

0.356

0.041

3.055

1.14

Chertow, 2010 [51]

245

0.533

0.184

1.546

4.65

Hotu, 2010 [52]

65

4.853

0.242

97.313

0.59

Yilmaz, 2010 [54]

112

0.333

0.014

8.011

0.52

Alvestrand, 2011 [56]

48

0.519

0.095

2.827

1.83

Chen, 2011 [57]

100

0.412

0.172

0.985

6.91

Rocco, 2011 [61]

87

1.867

0.176

19.836

0.94

Hur, 2013 [67]

156

0.500

0.094

2.651

1.89

Whalley, 2013 [68]

182

2.000

0.185

21.671

0.93

Ito, 2014 [70]

158

0.410

0.082

2.052

2.03

Mostovaya, 2014 [72]

714

0.799

0.544

1.174

35.67

Odudu, 2015 [74]

73

2.056

0.195

21.688

0.95

Higuchi, 2016 [75]

222

0.727

0.238

2.222

4.22

Lin, 2016 [77]

253

0.492

0.258

0.935

12.74

Liu, 2016 [76]

64

1.500

0.268

8.383

1.78

Jardine, 2017 [78]

200

2.500

0.497

12.585

2.01

Fujii, 2018 [85]

105

1.100

0.071

17.125

0.70

Miskulin, 2018 [79]

126

4.129

0.475

35.922

1.12

Marshall, 2020 [82]

99

2.041

0.191

21.786

0.94

Rutherford, 2021 [86]

80

0.400

0.082

1.942

2.11

Dorr, 2021 [84]

62

1.875

0.179

19.625

0.95

Pooleda

4367

0.717

0.570

0.902

100.00

Z = −2.84, P = 0.005, Ia = 0.0%, Q = 18.6, Pheterogeneity = 0.851

  1. CI confidence interval, N number, RR relative risk
  2. aPooled estimates are from random effects analysis. Results from the fixed effect analyses were the same