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Table 3 Comparison of the UPCR and NJ Equations in estimating measured 24-h urine protein

From: An equation to estimate 24-hour total urine protein excretion rate in patients who underwent urine protein testing

Variable and Equation

Training cohort

Validation cohort

RMSE (95% CI)

 UPCR

1.10 (1.03, 1.17)

1.02 (0.91, 1.12)

 NJ Equation

0.88 (0.82, 0.94)

0.81 (0.73, 0.89)

Bias (95% CI)

 UPCR

0.12 (0.11, 0.13)

0.12 (0.10, 0.13)

 NJ Equation

−0.010 (−0.020, −0.001)

−0.008 (−0.022, 0.004)

IQR (95% CI)

 UPCR

0.46 (0.43, 0.49)

0.47 (0.41, 0.53)

 NJ Equation

0.35 (0.33, 0.36)

0.34 (0.30, 0.36)

P30(%) (95% CI)

 UPCR

31.0 (29.4, 32.6)

32.2 (29.9, 34.5)

 NJ Equation

52.5 (50.8, 54.0)

53.4 (50.7, 56.1)

  1. RMSE root mean square error, CI confidence interval, UPCR urine protein-creatinine ratio, IQR interquartile range, P30 percentages of individuals that are within 30% difference
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BMC Nephrology

ISSN: 1471-2369

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