Skip to main content

Table 2 Factors associated with the use of therapeutic drug monitoring

From: Beta-lactam dosing during continuous renal replacement therapy: a survey of practices in french intensive care units

 

Use of therapeutic drug monitoring

 

Yes

n = (%)

No

n = (%)

p -value

Type of institution

  University hospital

45

33

0,569

  Other types of hospital

41

38

 

Years of experience ≤ 10

  Yes

48

48

0,493

  No

38

29

 

No adjustment of dosing regimens during CRRT

  Yes

48

45

0,425

  No

38

26

 

Do you adjust the dosage according to the dialysis dose or effluent flow?

  Yes

13

10

1,000

  No

72

59

 

Do you call other specialists for advice on antibiotic dosing regimen adjustments for patients on CRRT?

  Yes

47

18

<0,001

  No

18

53

 

Does your institution have procedures for adjusting antibiotic doses in patients on CRRT?

  Yes

17

16

0,821

  No

69

55

 

Do you use prolonged/continuous infusions for beta-lactams in patients on CRRT?

  Yes

81

57

0,016

  No

5

14

 
  1. The various groups were compared using Pearson’s chi-squared test with Yates’ correction. The threshold for statistical significance was set to p<0.05