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Table 2 Hospital Complications by AKI Stages for Patients Admitted with SARS-CoV2 Infection

From: SARS-CoV-2 infection increases risk of acute kidney injury in a bimodal age distribution

 

Total

No AKI

AKI-1

AKI − 2

AKI-3 (no RRT)

AKI-RRT

6874

4138 (60.2)

1733 (25.2)

382 (5.6)

517 (7.5)

104 (1.5)

Age Categories

  < 20 years

621 (9)

450 (11)

103 (6)

23 (6)

44 (9)

1 (1)

 20 to < 40 years

772 (11)

614 (15)

116 (7)

10 (3)

25 (5)

7 (7)

 40 to < 60 years

2038 (30)

1351 (33)

467 (27)

73 (19)

110 (21)

37 (36)

 60 to < 80 years

2647 (39)

1369 (33)

773 (45)

191 (50)

259 (50)

55 (53)

  ≥ 80 years

796 (12)

354 (9)

274 (16)

85 (22)

79 (15)

4 (4)

Admitted to ICU

 Yes

4075 (59)

2136 (52)

1116 (64)

282 (74)

437 (85)

104 (100)

 Noa

2799 (41)

2002 (48)

617 (36)

100 (26)

80 (16)

0 (0)

Hospitalization length of stay (days), median (IQR)b

7 (4, 13)

6 (4, 11)

9 (5, 17)

11 (6, 22)

13 (7, 23)

31 (22, 48)

ICU length of stay (days), median (IQR)b

5 (2, 11)

4 (2, 9)

6 (2, 13)

8 (2, 18)

6.5 (2.5, 16)

22 (11, 38)

Intubation

1899 (28)

720 (17.4)

596 (34)

185 (48)

298 (58)

100 (96)

Discharged on Oxygen

594 (9)

334 (8)

186 (11)

28 (7)

35 (7)

10 (10)

Vasopressors/ Inotropes

1203 (18)

380 (9)

374 (22)

134 (35)

222 (43)

93 (89)

ECMO

78 (1)

24 (0.6)

32 (2)

10 (3)

10 (2)

2 (2)

Thrombosesc

337 (5)

140 (3)

112 (7)

22 (6)

40 (8)

23 (22)

Mortality

1314 (19.1)

434 (10.5)

399 (23.0)

157 (41.1)

255 (49.3)

69 (66.4)

RD of Mortality (95% CI)

 

Reference

12.5% (10.3–14.7)

30.6% (25.6–35.6)

38.8% (34.4–43.2)

55.9% (46.7–65.0)

OR of Mortality (95% CI)

 

Reference

2.6 (2.2–3.0)

6.0 (4.7–7.5)

8.3 (6.8–10.1)

16.8 (11.1–25.6)

  1. Data presented as number (percentiles), except where specified. AKI Acute kidney injury, AKI-1 AKI stage 1, AKI-2 AKI stage 2, AKI-3 AKI stage 3, CI Confidence intervals, ECMO Extracorporeal membrane oxygenation, ICU Intensive care unit, OR Odds ratio, RRT Renal replacement therapy
  2. aOf those never admitted to the ICU, n = 139 died (5.0%) and n = 30 (1.1%) discharged to hospice care
  3. bLength of stay only among survivors (n = 5560). Hospital length of stay missing for 91 patients. Intensive care unit length of stay among only those who were ever admitted to ICU and survived (n = 2900). ICU length of stay missing for 81 patients
  4. cDefined by pre-selected categories of stroke, cerebrovascular accident, deep vein thromboses, and free text entry of the same plus thrombosis, clot, and pulmonary embolism