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Table 1 Response of ACE2 and TMPRSS2 to direct injurious stimuli in kidney and lung

From: Possible kidney-lung cross-talk in COVID-19: in silico modeling of SARS-CoV-2 infection

  

ACE2

TMPRSS2

Organ

Condition

FC

P-value

FC

P-value

LUNG

PMV

−1.71

0.00037

−1.69

0.00002

AKI 6 h

−1.86

0.00116

−1.43

0.00022

AKI 36 h

−2.56

0.00062

−1.27

NS

KIDNEY

PMV

1.05

NS

1.17

NS

AKI 6 ha

−2.44

0.00108

−1.76

0.01224

AKI 36 ha

−3.27

0.00033

1.03

NS

  1. a the data was extracted from supplemental materials Grigoryev et al [9]
  2. AKI acute kidney injury, PMV pneumonia and mechanical ventilation, FC fold change