Table 2 Gene candidates distantly upregulated in kidney or lung by injury to distant organ
From: Possible kidney-lung cross-talk in COVID-19: in silico modeling of SARS-CoV-2 infection
Gene | Symbol | lung during AKI | kidney in PMV | ||
|---|---|---|---|---|---|
FC | P value | FC | P value | ||
Lipocalin 2 | Lcn2 | 18.58 | 0.00020 | 6.32 | 0.00720 |
Suppressor of cytokine signaling 3 | Socs3 | 10.52 | 0.00018 | 10.36 | 0.00058 |
v-maf musculoaponeurotic fibrosarcoma oncogene family F | Maff | 7.21 | 0.00221 | 5.98 | 0.00091 |
Jun B proto-oncogene | Junb | 6.41 | 0.00023 | 5.37 | 0.00194 |
Inhibin beta-B | Inhbb | 6.20 | 0.00041 | 6.17 | 0.00102 |
Tumor necrosis factor receptor superfamily, member 12a | Tnfrsf12a | 6.09 | 0.00063 | 4.48 | 0.00081 |
Cholesterol 25-hydroxylase | Ch25h | 6.04 | 0.00040 | 4.30 | 0.00037 |
Metallothionein 2 | Mt2 | 5.29 | 0.00078 | 7.09 | 0.00003 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 | Hmgcs2 | 4.44 | 0.00877 | 5.31 | 0.00044 |