Association of significantly elevated plasma levels of NGAL and IGFBP4 in patients with diabetic nephropathy

BMC Nephrology

Table 3 Spearman’s rank correlation between IGFPBs and renal markers in the non-diabetic, T2D and DN groups

Study group	Markers	IGFBP-1		IGFBP-3		IGFBP-4
Study group	Markers	ρ	P value	ρ	P value	ρ	P value
Non-diabetic group	Serum Creatinine	- 0.039	0.807	- 0.176	0.270	0.302	0.052
	BUN	0.047	0.769	0.212	0.183	- 0.038	0.809
	eGFR	- 0.010	0.948	0.177	0.267	- 0.306	0.049
T2D group	Serum Creatinine	- 0.006	0.966	- 0.034	0.814	0.269	0.059
	BUN	0.160	0.267	0.002	0.991	- 0.013	0.927
	eGFR	- 0.141	0.334	- 0.036	0.794	−0.271	0.059
DN group	Serum Creatinine	- 0.249	< 0.05	0.178	0.150	0.397	< 0.001
	BUN	- 0.371	< 0.001	0.194	0.116	0.327	< 0.05
	eGFR	0.171	0.166	- 0.206	0.095	- 0.448	< 0.001

IGFBP Insulin-like growth factor binding protein −1,3,4, BUN blood urea nitrogen, eGFR glomerular filtration rate, Spearman’s correlation coefficient ρ and p-value are presented. The Association is considered statistically significant when p-value < 0.05

ISSN: 1471-2369