Table 2 Univariable and Multivariable Cox Regression Analysis of Rapid Kidney Function Decline
From: Nomogram to predict rapid kidney function decline in population at risk of cardiovascular disease
Variables | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
Adjusted HR (95%CI) | P value | Adjusted HR (95%CI) | P value | |
Age, years | 1.04 (1.03–1.05) | < 0.001 | 1.056 (1.044–1.068) | < 0.001 |
Female | 0.72(0.61–0.85) | < 0.001 | ||
Height, cm | 0.98 (0.97–0.99) | < 0.001 | ||
BMI, kg/m2 | 1.00 (0.99–1.03) | 0.600 | ||
SBP, mmHg | 1.01 (1.00–1.01) | < 0.001 | 1.007 (1.004–1.011) | 0.002 |
Diabetes mellitus | 1.99 (1.69–2.35) | < 0.001 | 1.902 (1.606–2.252) | 0.002 |
Hypertension | 1.56 (1.28–1.90) | < 0.001 | ||
eGFR, mL/min/1.73m2 | 1.02 (1.02–1.02) | < 0.001 | 1.022 (1.019–1.025) | < 0.001 |
Ever smoking | 0.65 (0.52–0.83) | < 0.001 | ||
Ever drinking | 0.65 (0.49–0.87) | 0.002 | ||
Hemoglobin | 0.98 (0.97–0.99) | < 0.001 | 0.985 (0.98–0.989) | 0.002 |
Cholesterol | 0.89 (0.83–0.96) | < 0.010 | ||
Uric acid | 1.00 (1.00–1.01) | < 0.001 | ||
ALT | 1.00 (1.00–1.00) | 0.500 | ||
BUN | 0.99 (0.97–1.01) | 0.400 | ||
Metformin | 2.04 (1.44–2.88) | < 0.001 | ||