Coexistence of diabetes mellitus and pre-existing cardiovascular disease and mortality in Chinese patients on peritoneal dialysis

Table 4 Associations between the coexistence of DM and CVD and mortality

	Model 1		Model 2		Model 3		Model 4
	HR	95%CI	HR	95%CI	HR	95%CI	HR	95%CI
All-cause mortality
Control group	Reference
Pre-existing CVD group	2.22	1.66 to 2.95	1.41	1.05 to 1.89	1.41	1.05 to 1.89	1.43	1.07 to 1.92
DM group	3.13	2.51 to 3.89	1.87	1.48 to 2.35	1.87	1.48 to 2.35	1.89	1.50 to 2.38
DM plus pre-existing CVD group	5.56	4.36 to 7.08	2.78	2.13 to 3.63	2.78	2.13 to 3.63	2.85	2.18 to 3.72
P values for trend		< 0.001		< 0.001		< 0.001		< 0.001
CVD mortality
Control group	Reference
Pre-existing CVD group	2.70	1.85 to 3.94	1.82	1.23 to 2.69	1.82	1.23 to 2.69	1.82	1.23 to 2.68
DM group	3.13	2.29 to 4.28	1.93	1.39 to 2.69	1.93	1.39 to 2.69	1.88	1.35 to 2.61
DM plus pre-existing CVD group	5.39	3.80 to 7.66	2.87	1.95 to 4.22	2.87	1.95 to 4.22	2.79	1.91 to 4.08
P values for tend		< 0.001		< 0.001		< 0.001		< 0.001

Model 1, unadjusted; model 2, model 1 plus age, sex, body mass index, systolic BP, diastolic BP, current smoking, current alcohol consumption, 24-h urine volume, hypertension, and hyperlipidemia; model 3, model 2 plus medications; model 4, model 3 plus hemoglobin, serum albumin, serum uric acid, eGFR, cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, and hs-CRP. DM diabetes mellitus, CVD cardiovascular disease, BP blood pressure, eGFR estimated glomerular filtration rate, hs-CRP high-sensitivity C-reactive protein, HR hazard ratio, CI confidence interval

ISSN: 1471-2369