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Table 1 The demographic and clinical data of all peritoneal dialysis patients

From: Patient-reported gastrointestinal symptoms in patients with peritoneal dialysis: the prevalence, influence factors and association with quality of life

Variables

Total

(n=471)

Non-gastrointestinal symptom group

(n=84)

Gastrointestinal symptoms group

(n=387)

P values

Age (years)

48.5±13.9

47.5±13.6

48.7±13.9

0.481

Male (n, %)

254(53.9%)

51(60.7%)

203(52.5%)

0.169

Primary renal disease (n, %)

   

0.173

 Glomerulonephritis

307(65.2%)

59(70.3%)

248(64.1%)

 

 Diabetic nephropathy

71(15.1%)

8(9.5%)

63(16.3%)

 

 Renal vascular diseases

39(8.3%)

10(11.9%)

29(7.5%)

 

 Other

54(11.5%)

7(8.3%)

47(12.1%)

 

Charlson comorbidity index (score)

3.0(2.0~4.0)

3.0(2.0~4.0)

3.0(2.0~5.0)

0.096

Duration of peritoneal dialysis (months)

37.3(17.5~66.5)

36.4(19.1~60.7)

38.0(16.7~67.5)

0.697

Total amount of pills per day (number)

14.0(9.0~21.0)

14.3(8.5~22.9)

14.0(9.0~21.0)

0.730

Use of proton pump inhibitor drugs (yes)

36(7.6%)

1(1.2%)

35(9.0%)

0.026

Use of gastrointestinal motility drugs (yes)

18(3.8%)

1(1.2%)

17(4.4%)

0.283

Use of phosphorus binders (yes)

195(41.4%)

30(35.7%)

165(42.6%)

0.243

Urine output (ml/d)

300.0(0.0~800.0)

540.0(15.0~1090.0)

250.0(0.0~700.0)

0.025

Peritoneal dialysis dose (ml/d)

8000.0(8000.0~10000.0)

8000.0(8000.0~10000.0)

8000.0(8000.0~10000.0)

0.776

Dwell volume of dialysate (ml)

2000.0(2000.0~2000.0)

2000.0(2000.0~2000.0)

2000.0(2000.0~2000.0)

0.114

Systolic blood pressure (mmHg)

135.8±22.1

137.7±19.5

135.4±22.6

0.383

Diastolic blood pressure (mmHg)

83.2±13.5

85.6±12.6

82.7±13.6

0.073

Body mass index (kg/m2)

22.2±3.2

22.5±3.3

22.1±3.2

0.395

Hemoglobin (g/L)

113.2±19.7

111.5±19.9

113.6±19.6

0.376

High-sensitivity C-reactive protein (mg/L)

1.6(0.6~5.0)

1.5(0.6~3.7)

1.7(0.6~5.3)

0.884

Serum albumin (g/L)

37.0±4.1

37.6±3.6

36.9±4.2

0.126

Serum calcium (mmol/L)

2.3±0.2

2.3±0.2

2.3±0.2

0.667

Serum phosphorus (mmol/L)

1.6±0.5

1.6±0.5

1.6±0.5

0.842

Intact parathyroid hormone (pg/ml)

330.7(157.6~651.7)

371.4(137.7~654.0)

328.9(160.4~651.7)

0.760

Total cholesterol (mmol/L)

4.9(4.2~5.7)

4.9(4.1~5.4)

4.9(4.2~5.7)

0.437

Triglycerides (mmol/L)

1.5(1.1~2.2)

1.5(1.0~2.4)

1.5(1.1~2.2)

0.878

Serum sodium (mmol/L)

138.3±3.9

138.3±3.0

138.3±4.1

0.907

Serum potassium (mmol/L)

4.1±0.7

4.2±0.6

4.1±0.7

0.350

Glycosylated hemoglobin (mmol/mol)

37.5±11.5

36.9±10.7

37.7±11.7

0.603

Blood urea nitrogen (mmol/L)

16.8(14.4~20.4)

17.1(14.3~21.1)

16.8(14.4~20.3)

0.550

Serum creatinine (umol/L)

1004(798~1223)

975.0(804.8~1339.0)

1006.0(795.0~1207.0)

0.560

Clearance index of urea

2.1(1.8~2.4)

2.2(1.7~2.5)

2.1(1.8~2.4)

0.356

Barthel index (score)

99.1±4.6

98.5±7.9

99.3±3.5

0.387

Instrumental activities of daily living scale (score)

22.7±3.8

22.8±4.2

22.6±3.7

0.772

Depression (score)

10.0(5.0~16.0)

8.0(4.0~14.8)

10.0(5.0~17.0)

0.033

Gastrointestinal symptom rating scale (score)

1.2(1.1~1.3)

-

1.2(1.1~1.4)

-

  Abdominal pain (score)

1.0(1.0~1.3)

-

1.0(1.0~1.3)

-

  Reflux (score)

1.0(1.0~1.0)

-

1.0(1.0~1.0)

-

  Dyspepsia (score)

1.3(1.0~1.5)

-

1.3(1.0~1.5)

-

  Constipation (score)

1.0(1.0~1.3)

-

1.0(1.0~1.7)

-

  Diarrhea (score)

1.0(1.0~1.0)

-

1.0(1.0~1.0)

-

  Eating disfunction (score)

1.0(1.0~1.0)

-

1.0(1.0~1.3)

-

Total score of quality of life (score)

60.0±17.8

60.6±19.2

59.9±17.5

0.724

  Physical Component Scale (score)

57.0±18.4

58.0±19.8

56.8±18.0

0.585

  Mental Component Scale (score)

63.0±19.7

63.3±20.6

63.0±19.5

0.897