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Table 6 The adjusted hazard ratio of cumulative input and output for 7-, 14-day mortalities

From: Early fluid management affects short-term mortality in patients with end-stage kidney disease undergoing chronic hemodialysis and requiring continuous renal replacement therapy

 

7-day mortality

14-day mortality

Model 1

Model 2

Model 1

Model 2

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Cumulative input on

3 day

0.96 (0.79—1.17)

0.71

0.85 (0.68—1.06)

0.53

1.01 (0.90—1.13)

0.92

0.98 (0.75—1.03)

0.78

Cumulative output on 3 day

0.67 (0.48—0.93)

0.01

0.66 (0.47—0.93)

0.04

0.78 (0.64—0.94)

0.01

0.79 (0.65—0.98)

0.03

     

Model 1

 

Model 2

     

HR (95% CI)

p-value

HR (95% CI)

p-value

Cumulative input on

7 day†

    

1.05 (0.97—1.14)

0.20

1.03 (0.94—1.13)

0.50

Cumulative output on 7 day†

    

0.84 (0.79—1.02)

0.09

0.91 (0.80—1.03)

0.14

  1. *per 1.0 L increase
  2. Subcohort who survived 7 days or more (n = 86)
  3. Model 1: Adjusted for age, sex, history of diabetes and hypertension
  4. Model 2: Adjusted for age, sex, history of diabetes and hypertension, use of vasopressor, Glasgow Coma Scale, Acute Physiology and Chronic Health Evaluation II scale, and duration of CRRT
  5. Abbreviation: HR Hazard ratio, CI Confidence interval