From: Erythropoietin in Acute Kidney Injury (EAKI): a pragmatic randomized clinical trial
Group without EPO | Group with EPO | |||||
---|---|---|---|---|---|---|
OR | 95%CI | p | OR | 95%CI | p | |
Age | 1.03 | 0.95,1.13 | 0.475 | 1.04 | 0.98,1.12 | 0.220 |
Gender Ref: Male | 0.75 | 0.15,3.64 | 0.721 | 3.45 | 0.81,14.74 | 0.095 |
Smoking | 4.17 | 0.79,21.84 | 0.091 | 0.32 | 0.06,1.64 | 0.172 |
Diabetes | 1.43 | 0.29,6.92 | 0.660 | 2.10 | 0.49,8.94 | 0.316 |
Previous CVD | 0.66 | 0.14,3.19 | 0.601 | 1.02 | 0.26,3.99 | 0.983 |
COPD | ||||||
Baseline eGFR | 0.99 | 0.96,1.04 | 0.970 | 1.01 | 0.99,1.04 | 0.361 |
AKI stage 2 or 3 Ref: AKI stage 1 | There was no death in stage 1 | 3.45 | 0.81,14.73 | 0.095 | ||
Hemoglobin T1 | 0.53 | 0.29,0.94 | 0.030 | 0.73 | 0.39,1.35 | 0.321 |
Serum creatinine T1 | 1.17 | 0.96,1.43 | 0.128 | 0.93 | 0.69,1.24 | 0.631 |
CRP T1 | 1.00 | 0.99,1.01 | 0.545 | 1.00 | 0.99,1.01 | 0.905 |
Ferritin | 1.00 | 0.99,1.005 | 0.911 | 1.001 | 0.99,1.005 | 0.638 |
Serum albumin | 0.91 | 0.81,1.02 | 0.113 | 0.92 | 0.83,1.02 | 0.109 |
Serum phosphate | 1.77 | 1.19,2.62 | 0.005 | 1.17 | 0.92,1.48 | 0.206 |
Serum bicarbonate | 0.86 | 0.74,0.98 | 0.027 | 1.05 | 0.93,1.19 | 0.425 |
Hemoglobin T2 | 0.46 | 0.27,0.78 | 0.004 | 0.82 | 0.51,1.32 | 0.421 |
CRP T2 | 1.01 | 1.00,1.03 | 0.034 | 1.02 | 1.00,1.03 | 0.019 |
Transfusions | 6.32 | 1.12,35.79 | 0.037 | 3.53 | 0.88,14.12 | 0.075 |
Full or partial renal recovery | 0.13 | 0.03,0.69 | 0.017 | 0.01 | 0.001,0.12 | < 0.001 |
Corticosteroid use | 1.71 | 0.35,8.43 | 0.511 | 4.59 | 1.03,20.53 | 0.046 |
Vasopressor use | 11.00 | 1.26,95.69 | 0.030 | 9.00 | 2.07,39.14 | 0.003 |