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Table 2 Anti-S1 IgG titres and response class at the end of the study

From: Response to three doses of the Pfizer/BioNTech BNT162b2 COVID-19 vaccine: a retrospective study of a cohort of haemodialysis patients in France

Variable

Value

Anti-S1 IgG (participants with three doses of vaccine), U/ml (n = 97; all but one were COVID-19-negative in a PCR test)

 mean (SD)

170.06 (212.12)

 median [IQR]

93.26 [34.25; 176.06]

 range

(0.0; 750.0)

Anti-S1 IgG (COVID-19-positive participants), U/ml (n = 15)

 mean (SD)

351.4 (352.0)

 median [IQR]

294.9 (4.2; 750.0)

 range

2.5; 750.0

Response class in COVID-19-negative patients with two doses of vaccine, n (%) (n = 7)

 Non-responders (< 0.8 U/ml)

0

 Borderline (0.8 to 1.2 U/ml)

2 (28.6%)

 Responders (≥1.2 U/ml)

5 (71.4%)

Response class in COVID-19-negative patients with three doses of vaccine, n (%) (n = 96)

 Non-responders (< 0.8 U/ml)

0

 Borderline (0.8 to 1.2 U/ml)

4 (4.2%)

 Responders (≥1.2 U/ml)

92 (95.8%)

Response class in patients with three doses (whatever the COVID-19 status), n (%) (n = 97)

 Non-responders (< 0.8 U/ml)

0

 Borderline (0.8 to 1.2 U/ml)

4 (4.1%)

 Responders (≥1.2 U/ml)

93 (95.9%)

  1. S1 Spike, IgG Immunoglobulin G, COVID-19 Coronavirus disease 2019, PCR Polymerase chain reaction, SD Standard deviation, IQR Interquartile range