Table 2 Hazard ratios (HRs) (95% CI) on all-cause mortality and ESKD (univariate and multivariate analysis)

DM at least

1.49(1.21–1.83)

0.0002

1.49(1.31–1.7)

< 0.0001

1.46(1.13–1.88)

0.004

1.77(1.49–2.10)

< 0.0001

Hyperuricemia at least

1.39(1.1–1.75)

0.0058

1.71(1.48–1.99)

< 0.0001

1.44(1.09–1.91)

0.0114

1.43(1.19–1.73)

0.0002

Age

1.06(1.05–1.07)

< 0.0001

0.97(0.97–0.98)

< 0.0001

1.05(1.04–1.06)

< 0.0001

0.97(0.97–0.98)

< 0.0001

Gender

(male v.s. female)

1.46(1.16–1.84)

0.0012

0.65(0.58–0.74)

< 0.0001

0.96(0.67–1.37)

0.8161

1.01(0.82–1.24)

0.9394

Ever smoker

(yes v.s. no)

1.74(1.41–2.14)

< 0.0001

0.9(0.78–1.03)

0.1124

1.58(1.16–2.16)

0.0042

1.16(0.95–1.43)

0.1537

CKD stage

(stage4 v.s. stage3)

1.61(1.27–2.05)

< 0.0001

4.13(3.33–5.14)

< 0.0001

1.88(1.42–2.49)

< 0.0001

4.33(3.29–5.70)

< 0.0001

CKD stage

(stage5 v.s. stage3)

1.56(1.19–2.05)

0.0015

22.43(18.29–27.52)

< 0.0001

1.85(1.30–2.63)

0.0007

24.16(18.59–31.38)

< 0.0001

Mean SBP (mmHg)

1(0.99–1.00)

0.3511

1.02(1.02–1.03)

< 0.0001

1(0.99–1.00)

0.2826

1.02(1.01–1.02)

< 0.0001

Medications for hyperuricemia

(yes v.s. no)

1.33(1.07–1.65)

0.0105

0.93(0.80–1.07)

0.2845

1.2(0.92–1.56)

0.1828

0.84(0.70–1.02)

0.0746

Statin

(yes v.s. no)

0.71(0.56–0.90)

0.004

1.08(0.94–1.24)

0.2621

0.67(0.50–0.90)

0.0085

1.18(0.99–1.40)

0.0646

ACEi or ARB

(yes v.s. no)

1.02(0.82–1.26)

0.8836

1.03(0.91–1.18)

0.6346

1.13(0.87–1.47)

0.3488

0.94(0.80–1.12)

0.4984