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Table 1 Baseline characteristics

From: Epidemiology and outcomes in patients with anemia of CKD not on dialysis from a large US healthcare system database: a retrospective observational study

 

All patients

(N = 50,701)a

Patients with anemia

(N = 11,673)

Patients without anemia

(N = 35,033)

Sex, n (%)

 Female

28,450 (56.1)

7175 (61.5)

19,116 (54.6)

Mean age, years (SD)

72.0 (13.1)

71.2 (14.4)

72.2 (12.8)

Age group, n (%)

  < 50 years

2758 (5.4)

917 (7.9)

1715 (4.9)

 50–59 years

5613 (11.1)

1425 (12.2)

3835 (10.9)

 60–69 years

11,969 (23.6)

2645 (22.7)

8271 (23.6)

 70–79 years

14,372 (28.3)

2913 (25.0)

10,043 (28.7)

  ≥ 80 years

15,989 (31.5)

3773 (32.3)

11,169 (31.9)

Race, n (%)

 African American

13,637 (26.9)

3559 (30.5)

8927 (25.5)

 Asian

543 (1.1)

96 (0.8)

406 (1.2)

 Hispanic

888 (1.8)

245 (2.1)

584 (1.7)

 White

31,975 (63.1)

7085 (60.7)

22,530 (64.3)

 Other/unknown

3658 (7.2)

688 (5.9)

2586 (7.4)

CKD stage, n (%)b

 3a

30,204 (59.6)

4979 (42.7)

22,444 (64.1)

 3b

13,882 (27.4)

3548 (30.4)

9386 (26.8)

 4

4880 (9.6)

2050 (17.6)

2597 (7.4)

 5

1735 (3.4)

1096 (9.4)

606 (1.7)

Hb stratac g/dL, n (%)

  < 8.0

4147 (8.2)

4147 (35.5)

–

 8.0–9.9

7526 (14.8)

7526 (64.5)

–

 10.0–12.0

15,196 (30.0)

–

15,196 (43.4)

  > 12.0

19,837 (39.1)

–

19,837 (56.6)

 Missing

3995 (7.9)

–

–

Anemia therapy, n (%)

 ESA

539 (1.1)

483 (4.1)

53 (0.2)

 Iron (IV and oral)

4283 (8.4)

2825 (24.2)

1410 (4.0)

 RBC transfusion

1306 (2.6)

1287 (11.0)

19 (0.1)

 Any of the above

5219 (10.3)

3703 (31.7)

1468 (4.2)

  1. aIncluded patients with anemia, without anemia, and those for whom no Hb measurement was available in the baseline period. The latter group of patients were excluded from the anemia and non-anemia cohorts
  2. bCKD stages based on eGFR measurements (mL/min per 1.73 m2): 3a, 45–59; 3b, 30–44; 4, 15–29; 5, < 15
  3. cHb level/anemia status was determined from the lowest available Hb level during the 6 months pre/post index date
  4. CKD chronic kidney disease, ESA erythropoiesis-stimulating agent, Hb hemoglobin, IV intravenous, RBC red blood cell, SD standard deviation