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Fig. 2 | BMC Nephrology

Fig. 2

From: Targeting inflammation for the treatment of Diabetic Kidney Disease: a five-compartment mechanistic model

Fig. 2

Five-compartment model of impairment due to chronic inflammation in diabetic kidney disease. Conceptual model of five functional and structural compartments that can be affected by immunopathology in patients with diabetic kidney disease. The model provides a framework for linking pre-clinical models of disease pathways with predominant immunopathology in particular patient types. Stratification of patients based on predominant immunopathology in the five-compartment model may enable targeting of the right treatments to the right patients

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