Fig. 3

Immunofluorescence microscopy of kidney biopsy (original magnification 400x): Diffuse global granular mesangial and capillary wall deposition of A IgG (2+ intensity, on a scale of 0–3+), B IgA (2–3+), C IgM (3+); D C3 (2–3+), E C1q (3+) and F fibrinogen (3+). Fibrinogen was predominantly detected in the crescentic area (white curved arrows), indicating passage of plasma material to Bowman’s space due to rupture of glomerular basement membrane in the process of fibrinoid necrosis