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Fig. 2 | BMC Nephrology

Fig. 2

From: Statins attenuate cholesterol-induced ROS via inhibiting NOX2/NOX4 and mitochondrial pathway in collecting ducts of the kidney

Fig. 2

A ROS production was detected in cholesterol overload primary IMCD suspensions with or without simvastatin. B Cell survival ratio of mpkCCD cells treated with simvastatin for 24 h assessed by CCK. C Immunofluorescence images showed that simvastatin reduced cholesterol induced intracellular ROS production in mpkCCD cells. D ROS production in cholesterol-treated mpkCCD cells with or without simvastatin were quantified by flow cytometry

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BMC Nephrology

ISSN: 1471-2369

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