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Fig. 3 | BMC Nephrology

Fig. 3

From: Statins attenuate cholesterol-induced ROS via inhibiting NOX2/NOX4 and mitochondrial pathway in collecting ducts of the kidney

Fig. 3

A and B Protein abundance of NOX2, NOX4, and Cleaved-caspase3 were detected by western blotting and corresponding semiquantitative densitometry analysis in cholesterol-treated mpkCCD cells with or without simvastatin treatment. C Immunofluorescence of NOX2 and NOX4 in cholesterol-treated mpkCCD cells with or without simvastatin treatment. D mRNA level of NOX2, NOX4, NOS2, and NOS3 in cholesterol-treated mpkCCD cells with or without simvastatin treatment. *P < 0.05 compared with CTL. #P < 0.05 compared with Cholesterol. Scale bars, 10 μm

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BMC Nephrology

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