Elevated parathyroid hormone one year after kidney transplantation is an independent risk factor for graft loss even without hypercalcemia

Table 2 Risk factors for death-censored graft loss

	Univariate analysis			Multivariate analysis
	P-value	HR	95% CI	P-value	HR	95% CI
Male recipient	0.129	1.403	0.906–2.173
Male donor	0.397	0.829	0.538–1.279
Recipient age (years)	0.349	0.993	0.978–1.008
Donor age (years)	0.020*	1.025	1.004–1.048	0.550	1.007	0.983–1.032
Body mass index (kg/m²)	0.005*	1.075	1.022–1.130	0.034*	1.060	1.004–1.119
Dialysis vintage (months)	0.459	1.002	0.997–1.006
Preemptive KTx	0.399	0.817	0.511–1.307
Diabetes mellitus	0.028	1.719	1.061–2.785	0.514	1.192	0.704–2.018
Deceased donor KTx	0.843	1.123	0.355–3.552
HLA AB mismatch	0.733	0.966	0.792–1.179
HLA DR mismatch	0.910	0.981	0.701–1.372
Preformed DSA	0.003*	3.117	1.485–6.546	0.007*	2.834	1.331–6.034
ABO blood type Incompatible KTx	0.240	1.322	0.830–2.106	0.722	1.089	0.682–1.738
Corrected calcium at one year post KTx (mg/dL)	0.542	0.840	0.480–1.472
Phosphorus at one year post KTx (mg/dL)	< 0.001*	1.705	1.298–2.241	0.009*	1.501	1.106–2.038
eGFR at one year post KTx (mL/min/1.73m²)	< 0.001*	0.953	0.935–0.972	0.004*	0.971	0.951–0.991
NC-HPT	< 0.001*	2.290	1.518–3.457	0.002*	1.944	1.268–2.980

DSA Donor-specific HLA antibody, eGFR Estimated glemerular filtration rate, HPT Hyperparathyroidism, NC-HPT Normocalcemic hyperparathyroidism, PTH Parathyroid hormone, KTx Kidney transplantation
* P-value < 0.05

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