Table 3 Univariate Cox regression analysis of prognostic factors for cardiovascular mortality

Total Indoxyl Sulfate(≥44.16 vs < 44.16 μg/ml)

2.18(1.38–3.46)

< 0.01

Total Indoxyl Sulfate (Continuous)

1.02(1.01–1.03)

< 0.01

Age, years

1.05(1.04–1.07)

0.01

Gender (Female vs Male)

1.04(0.74–1.46)

0.84

Time on dialysis, months

1.002(0.998–1.006)

0.33

Diabetic nephropathy

2.99(2.12–4.22)

< 0.01

Glomerulonephritis

0.28(0.18–0.43)

< 0.01

Hypertensive benign renal arteriosclerosis

1.56(1.06–2.29)

0.02

Polycystic kidney

0.88(0.43–1.81)

0.73

Hemoglobin, g/l

0.997(0.986–1.008)

0.58

Alanine aminotransferase,u/L

1.001(1.000–1.002)

0.12

Albumin, g/l

0.84(0.78–0.89)

< 0.01

Alkaline phosphatase, u/l

1.001(1.000–1.002)

0.14

Urea nitrogen, mmol/L

0.99(0.96–1.02)

0.46

Creatinine, umol/L

0.998(0.998–0.999)

< 0.01

Kt/V

0.46(0.22–0.95)

0.04

Platelet, (×10⁹/L)

1.001(0.998–1.004)

0.48

Potassium, mmol/L

1.04(0.84–1.29)

0.73

Sodium, mmol/l

0.92(0.87–0.96)

< 0.01

Calcium, mmol/l

0.69(0.26–1.86)

0.46

Phosphorus, mmol/l

0.96(0.71–1.30)

0.79

Chlorine, mmol/l

0.95(0.91–0.99)

0.02