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Table 5 Multivariable Cox regression analysis of prognostic factors for cardiovascular mortality

From: Serum total indoxyl sulfate levels and all-cause and cardiovascular mortality in maintenance hemodialysis patients: a prospective cohort study

Characteristic

HR (95% CI)

P

HR (95% CI)

P

Total Indoxyl Sulfate(≥44.16 vs < 44.16 μg/ml)

1.76(1.10–2.82)

0.02

Total Indoxyl Sulfate (Continuous)

1.02(1.01–1.03)

< 0.01

Age, years

1.04(1.02–1.06)

< 0.01

1.04(1.03–1.06)

< 0.01

Diabetic nephropathy

2.68(1.39–5.19)

< 0.01

2.58(1.33–4.99)

< 0.01

Glomerulonephritis

0.97(0.48–2.00)

0.94

0.93(0.45–1.90)

0.84

Hypertensive benign renal arteriosclerosis

1.86(0.94–3.67)

0.07

1.76(0.89–3.47)

0.10

Albumin, g/l

0.90(0.83–0.97)

< 0.01

0.91(0.84–0.98)

0.02

Creatinine, umol/L

1.00(0.999–1.001)

0.84

1.00(0.999–1.001)

0.75

Kt/V

0.40(0.17–0.95)

0.04

0.40(0.17–0.94)

0.04

Sodium, mmol/l

0.99(0.93–1.07)

0.88

0.98(0.92–1.06)

0.65

Chlorine, mmol/l

0.96(0.90–1.02)

0.17

0.97(0.91–1.03)

0.20

  1. All statistical tests are two sided
  2. Abbreviation: CI confidence interval, HR hazards ratio