Fig. 2

1,25-dihydroxyvitamin D3 reduced proteinuria and protected renal function. A MRL/lpr mice in the control groups. B MRL/lpr mice in the VitD3-treated groups. C The body weight of the experimental MRL/lpr mice. D Urine protein time-course studies. E Serum creatinine levels. F Blood urea nitrogen levels. Values are expressed as means ± SD (n = 6/group). & VS. mice at the previous week. * VS. the control group at the same time. # VS. the control group at 14 weeks. △VS. the treated group at 14 weeks. ^*#△& p < 0.05, ^**##△△&&p < 0.01, ^{***###△△△&&&}p < 0.001, ^&&&&P<0.0001