Table 2 Demographic and renal characteristics of 20 patients with Crohn’s disease referred for kidney biopsy

Patients — no

20

Male sex — no. (%)

11 (55%)

Age at kidney biopsy — yr

33.50±14.56

Age distribution at kidney biopsy (yr) — no. (%)

  < 20

3 (15%)

 20–30

6 (30%)

 30–40

7 (35%)

 40–50

1 (5%)

 50–60

1 (5%)

  ≥ 60

2 (10%)

Body mass index — Kg/m²

19.93±2.84

Systolic blood pressure — mmHg

110.60±13.17

Diastolic blood pressure — mmHg

71.50±7.16

Serum albumin — g per L

37.32±6.65

Serum creatinine — umol per L

115.589±113.71

Blood urea nitrogen — mmol per L

6.38±4.40

eGFR^a — ml per min per 1.73m²

99.77±44.30

eGFR^a category — no. (%)

  ≥ 90 ml per min per 1.73m²

14 (70%)

  60–89.9 ml per min per 1.73m²

3 (15%)

   < 60 ml per min per 1.73m²

3 (15%)

Urine PH

6.28±0.82

Urinary protein excretion — g per 24 h

0.84±1.25

Degree of proteinuria (g per 24 h) — no. (%)

  ≤ 0.2

7 (35%)

  > 0.2 to < 2.0

10 (50%)

  ≥ 2.0 to < 3.5

1 (5%)

  ≥ 3.5 to < 5.0

2 (10%)

  ≥ 5.0 to 10.0

0 (0%)

  ≥ 10.0

0 (0%)

Hematuria — no. (%)

17 (85%)

Nephrolithiasis — no. (%)

2 (10%)

Indication for kidney biopsy — no. (%)

 Nephrotic-range proteinuria

2 (10%)

 Subnephrotic proteinuria

6 (30%)

 Persistent hematuria and proteinuria

5 (25%)

 Isolated hematuria with acanthocytes

5 (25%)

 Impaired kidney function (serum creatinine > 1.5 mg/dl)

2 (10%)

RAS inhibitors — no. (%)

5 (25%)

 Steroids to treat renal disease — no. (%)

7 (35%)

 Steroids intravenously — no. (%)

6 (30%)

 Steroids combined with immunosuppressive agents to treat renal disease — no. (%)

1 (5%)