Table 1 Comparison of clinical characteristics between the two groups at the time of renal biopsy
From: The clinical and pathological characteristics of IgA nephropathy patients in Tibet
Tibetan group (n = 80) | Beijing group (n = 991) | P Value | |
|---|---|---|---|
Ethnicity (Han/Tibetan) | 1/79 | 990/1 | < 0.001 |
Gender (M/F) | 48/32 | 527/464 | 0.239 |
Age (years) | 32.6 ± 12.4 | 39.12 ± 12.6 | < 0.001 |
SBP (mmHg) | 135.7 ± 24.6 | 129.3 ± 16.3 | 0.043 |
DBP (mmHg) | 91.2 ± 17.9 | 80.9 ± 11.7 | < 0.001 |
MAP (mmHg) | 106.0 ± 19.0 | 97.0 ± 12.6 | < 0.001 |
HGB (g/L) | 158.6 ± 83.8 | 126.3 ± 20.9 | < 0.001 |
PLT (10^9/L) | 239.8 ± 89.7 | 239.2 ± 68.5 | 0.77 |
ALB (g/L) | 30.4 ± 7.7 | 38.2 ± 5.5 | < 0.001 |
UTP (g/day) | 2.9 [2.0, 4.9] | 1.1 [0.5, 2.4] | < 0.001 |
Nephrotic syndrome | 27/80 (33.8%) | 47/991 (4.7%) | < 0.001 |
eGFR (ml/min/1.73 m2) | 77.7 ± 37.8 | 62.1 ± 33.6 | 0.001 |
UA (μmol/L) | 424.1 ± 109.1 | 414.4 ± 115.2 | 0.401 |
CaAlb (mmol/L) | 2.28 ± 0.33 | 2.33 ± 0.17 | 0.017 |
P (mmol/L) | 1.30 ± 0.29 | 1.17 ± 0.27 | < 0.001 |
Serum IgG (g/L) | 8.66 [5.41, 12.62] | 10.30 [8.49, 12.50] | 0.025 |
Serum IgA (g/L) | 2.80 [2.29, 3.92] | 3.13 [2.38, 3.91] | 0.54 |
Serum IgM (g/L) | 1.14 [0.92, 1.53] | 0.94 [0.68, 1.33] | 0.003 |
Serum C3 (g/L) | 1.18 [1.04, 1.47] | 0.85 [0.74, 0.98] | < 0.001 |
Serum C4 (g/L) | 0.27 [0.21, 0.34] | 0.24 [0.20, 0.29] | 0.066 |
Serum C3/C4 | 4.44 [3.84, 5.61] | 3.60 [3.06, 4.15] | < 0.001 |
Serum IgA/C3 | 2.52 [1.89, 3.16] | 3.58 [2.74, 4.63] | < 0.001 |