Table 2 Correlation of inflammation-related biomarkers with variables at diagnosis in AAV patients (N = 76)
Variables at diagnosis | Correlation Coefficient (r, (P-value)) | ||
|---|---|---|---|
New biomarkers | GA | HbA1c | GA/HbA1c |
AAV-specific indices | |||
BVAS | 0.116 (0.318) | 0.040 (0.732) | 0.090 (0.437) |
FFS | 0.282 (0.019) | 0.069 (0.573) | 0.209 (0.085) |
Clinical manifestations (Score assigned to each manifestation) | |||
General manifestations | 0.164 (0.156) | 0.118 (0.308) | 0.085 (0.463) |
Cutaneous manifestations | -0.178 (0.123) | 0.014 (0.907) | -0.159 (0.170) |
Mucous and ocular manifestations | -0.051 (0.660) | 0.046 (0.693) | -0.072 (0.536) |
Otorhinolaryngologic manifestations | -0.082 (0.483) | 0.033 (0.777) | -0.091 (0.434) |
Pulmonary manifestations | -0.142 (0.221) | -0.118 (0.311) | -0.058 (0.618) |
Cardiovascular manifestations | 0.050 (0.669) | 0.011 (0.923) | 0.035 (0.767) |
Gastrointestinal manifestations | N/A | N/A | N/A |
Renal manifestations | 0.315 (0.006) | -0.024 (0.834) | 0.310 (0.006) |
Nervous systemic manifestations | -0.088 (0.448) | 0.182 (0.116) | -0.190 (0.101) |
Acute phase reactants | |||
ESR (mm/hr) | 0.146 (0.210) | 0.048 (0.684) | 0.094 (0.420) |
CRP (mg/L) | 0.124 (0.302) | -0.016 (0.894) | 0.133 (0.270) |
Laboratory results | |||
White blood cell count (/mm3) | -0.221 (0.055) | 0.013 (0.914) | -0.226 (0.050) |
Haemoglobin (g/dL) | -0.345 (0.002) | 0.116 (0.317) | -0.416 (< 0.001) |
Platelet count (× 1000/mm3) | 0.031 (0.790) | -0.113 (0.331) | 0.105 (0.365) |
Blood urea nitrogen (mg/dL) | 0.382 (0.001) | -0.158 (0.175) | 0.487 (< 0.001) |
Serum creatinine (mg/dL) | 0.188 (0.107) | -0.128 (0.273) | 0.277 (0.016) |
Total protein (g/dL) | 0.119 (0.309) | -0.024 (0.838) | 0.094 (0.424) |
Serum albumin (g/dL) | 0.077 (0.512) | -0.067 (0.567) | 0.103 (0.381) |
Random urine protein/creatinine ratio | 0.095 (0.439) | -0.076 (0.536) | 0.152 (0.217) |
Red blood cells per high power field | 0.055 (0.646) | -0.043 (0.720) | 0.067 (0.517) |