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Table 7 Relationship between Hb and renal prognosis and renal function decline in different sensitivity analyses

From: Association between hemoglobin and chronic kidney disease progression: a secondary analysis of a prospective cohort study in Japanese patients

Exposure

Model I(HR,95%CI, P)

Model II (β,95%CI, P)

eGFR ≥ 15(ml/min per 1.73 m2)

 Hb

0.837 (0.757, 0.926) 0.00053

-0.408 (-0.789, -0.027) 0.03608

Hb Quartile

 Q1

Ref

Ref

 Q2

0.928 (0.586, 1.470) 0.75033

0.680 (-1.351, 2.711) 0.51203

 Q3

0.600 (0.352, 1.021) 0.05944

-0.009 (-2.116, 2.097) 0.99313

 Q4

0.380 (0.193, 0.748) 0.00508

-1.789 (-4.141, 0.563) 0.13641

 P for trend

0.00195

0.07496

UPCR < 0.5 g/gCr

 Hb

0.622 (0.474, 0.815) 0.00058

-0.201 (-0.625, 0.223) 0.35305

Hb Quartile

 Q1

Ref

Ref

 Q2

0.380 (0.140, 1.029) 0.05683

0.956 (-1.518, 3.429) 0.44930

 Q3

0.172 (0.044, 0.678) 0.01188

0.014 (-2.370, 2.398) 0.99059

 Q4

0.145 (0.022, 0.946) 0.04357

-0.396 (-3.061, 2.269) 0.77110 0.49540

 P for trend

0.0066

 
  1. Model I was a sensitivity analysis of the relationship between Hb and renal prognosis. We adjusted age, gender, BMI, SBP, hypertension, diabetes, history of CVD, UPCR, eGFR, ALB, urinary occult blood, use of RAAS inhibitor, use of calcium channel blocker, use of diuretics
  2. Model II was a sensitivity analysis of the relationship between Hb and kidney function decline. We adjusted age, gender, BMI, SBP, hypertension, diabetes, history of CVD, UPCR, eGFR, ALB, urinary occult blood, use of RAAS inhibitor, use of calcium channel blocker, use of diuretics
  3. HR Harzard ratios, CI Confidence, Ref Reference
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BMC Nephrology

ISSN: 1471-2369

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