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Table 2 Cause of diagnosis, co-morbidity and therapeutic characteristics of the study patients

From: Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana

Variables

All patients

Renal replacement therapy group

Conservative group

P-value

 

N (%)

N (%)

N (%)

 

Cause of diagnosis

    

CGN

119(31.4)

12(20.3)

107(33.4)

< 0.001

Hypertension

115(30.3)

19(32.2)

96(30.0)

< 0.001

Diabetes mellitus nephropathy

107(28.2)

24(40.7)

83(25.9)

< 0.001

HIVAN

12(3.2)

0(0.0)

12(3.8)

-

ADPKD

10(2.6)

3(5.1)

7(2.2)

0.206

Obstructive uropathy

8(2.1)

1(1.7)

7(2.2)

0.034

Othersa

8(2.1)

0(0.0)

8(2.5)

-

Co-morbid at the time of presentation

Hypertension

169(57.3)

31(59.6)

138(56.8)

< 0.001

Diabetes mellitus

20(6.8)

4(7.7)

16(6.6)

0.007

Hypertension with Diabetes Mellitus

85(28.8)

17(32.7)

68(28.0)

< 0.001

HIV

13(4.4)

0(0.0)

13(5.3)

-

Othersb

8(2.7)

0(0.0)

8(3.3)

-

Medications (yes)

Nifedipine

288(75.4)

50(82.0)

238(74.1)

< 0.001

Irbesartan/Lisinopril

218(57.1)

32(52.5)

186(57.9)

< 0.001

Bisoprolol

61(16.0)

20(32.8)

41(12.8)

0.007

Aspirin

41(10.7)

12(19.7)

29(9.0)

0.008

Prednisolone

14(3.7)

4(6.6)

10(3.1)

0.109

Ranitidine

70(18.3)

16(26.2)

54(16.8)

< 0.001

Metformin

34(8.9)

8(13.1)

26(8.1)

0.002

Gliclazide

382(100.0)

61(100.0)

321(100.0)

< 0.001

Lasix

295(77.2)

48(78.7)

247(76.9)

< 0.001

Hydralazine

139(36.4)

32(52.5)

107(33.3)

< 0.001

Methyldopa

191(50.0)

32(55.7)

157(48.9)

< 0.001

EPO

35(9.2)

17(27.9)

18(5.6)

0.866

CaCO3

242(63.4)

39(63.9)

203(63.2)

< 0.001

NaHCO3

193(50.5)

26(42.6)

167(52.0)

< 0.001

Statin

92(24.1)

19(31.1)

73(22.7)

< 0.001

  1. CGN: chronic glomerulonephritis, HIVAN: HIV associated nephropathy, HIV: human immunodeficiency virus, ADPKD: autosomal dominant polycystic kidney disease, EPO: erythropoietin, CaCO3: Calcium carbonate, NaHCO3: Sodium hydro carbonate, Othersa : Benign Prostatic Hyperplasia, Bilateral Vascular Failure, Diabetes Mellitus/Sickle Cell, Hepatitis B/HIV, Hypertension/Stroke, Sickle cell, Othersb : Chronic Interstitial nephritis, Chronic schistosomiasis, HIV, Multiple myeloma, Renal oncocytoma, Uremic gastritis, SC nephropathy