CKD without HTN/T2D | CKD with HTN | CKD with T2D | CKD with HTN/T2D | p-value | ||
---|---|---|---|---|---|---|
Age (years) | 70 [58, 80] | 76 [68, 82] | 69 [57, 78] | 74 [65, 80] | < 0.001 | |
Age (years, cat.) | < 65 | 39.74 | 20.61 | 42.61 | 25.30 | < 0.001 |
(65, 80) | 37.01 | 47.97 | 38.19 | 51.22 | ||
≥ 80 | 23.24 | 31.42 | 19.20 | 23.48 | ||
Sex | Female | 56.55 | 59.03 | 38.94 | 50.27 | < 0.001 |
MEDEA deprivation index | Rural | 24.43 | 25.52 | 23.40 | 24.53 | < 0.001 |
Least deprived quintile | 18.13 | 16.07 | 13.35 | 12.91 | ||
Second quintile | 16.05 | 15.34 | 15.11 | 14.27 | ||
Third quintile | 14.95 | 15.36 | 14.57 | 15.53 | ||
Forth quintile | 13.90 | 14.57 | 15.87 | 16.27 | ||
Most deprived quintile | 12.54 | 13.14 | 17.70 | 16.49 | ||
Expanded CHARLSON INDEX SCORE | Non comorbidity | 64.57 | 68.31 | 54.05 | 51.05 | < 0.001 |
Low | 29.38 | 26.47 | 34.88 | 37.08 | ||
High | 6.05 | 5.21 | 11.08 | 11.87 | ||
Opht/ neur complications | 0.07 | 0.27 | 10.33 | 13.53 | < 0.001 | |
Hypertensive heart disease | 0.00 | 2.71 | 0.00 | 3.16 | < 0.001 | |
Other specified kidney diseases | 3.43 | 2.28 | 2.32 | 2.09 | < 0.001 | |
Autoimmune Disease with CKD risk | 0.59 | 0.34 | 0.38 | 0.20 | < 0.001 | |
Smoking status | Non smoker | 66.20 | 72.30 | 53.90 | 65.28 | < 0.001 |
Smoker | 17.10 | 11.37 | 23.47 | 13.54 | ||
Former smoker | 16.70 | 16.34 | 22.63 | 21.18 | ||
Obesity | Underweight | 1.53 | 0.42 | 0.63 | 0.16 | < 0.001 |
Normal | 31.64 | 17.78 | 20.22 | 11.85 | ||
Overweight | 43.64 | 43.31 | 43.21 | 38.72 | ||
Class 1 obesity | 17.96 | 27.41 | 25.16 | 31.29 | ||
Class 2/3 obesity | 5.23 | 11.08 | 10.78 | 17.98 | ||
Heart Failure | 4.60 | 6.02 | 6.42 | 7.83 | < 0.001 | |
Atrial Fibrillation | 6.97 | 9.83 | 8.10 | 10.49 | < 0.001 | |
Hypercholesterolemia | 44.20 | 43.29 | 29.23 | 27.36 | < 0.001 | |
Systolic blood pressure | ≥ 140 mm Hg | 14.93 | 37.03 | 16.78 | 42.95 | < 0.001 |
Diastolic blood pressure | ≥ 90 mm Hg | 4.83 | 9.81 | 4.06 | 9.74 | < 0.001 |
Anemia | 17.10 | 18.04 | 20.66 | 24.29 | < 0.001 | |
Statins | 30.91 | 41.49 | 49.50 | 59.70 | < 0.001 | |
Platelet / Anticoagulant | 22.64 | 32.40 | 38.54 | 51.57 | < 0.001 | |
Angiotensin-converting enzyme inh. | 12.63 | 57.18 | 23.42 | 63.59 | < 0.001 | |
Angiotensin II receptor antagonists | 7.09 | 36.01 | 11.84 | 43.37 | < 0.001 | |
Aldosterone antagonists | 4.21 | 4.06 | 6.82 | 5.89 | < 0.001 |