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Table 1 Baseline characteristics of the KIDNEES cohort free of Atherosclerotic Cardiovascular Disease at baseline (n = 398,477) (pooled imputed data)

From: Cardiovascular events and mortality in chronic kidney disease in primary care patients with previous type 2 diabetes and/or hypertension. A population-based epidemiological study (KIDNEES)

  

CKD without HTN/T2D

CKD with HTN

CKD with T2D

CKD with HTN/T2D

p-value

Age (years)

 

70 [58, 80]

76 [68, 82]

69 [57, 78]

74 [65, 80]

< 0.001

Age (years, cat.)

< 65

39.74

20.61

42.61

25.30

< 0.001

(65, 80)

37.01

47.97

38.19

51.22

 

≥ 80

23.24

31.42

19.20

23.48

 

Sex

Female

56.55

59.03

38.94

50.27

< 0.001

MEDEA deprivation index

Rural

24.43

25.52

23.40

24.53

< 0.001

Least deprived quintile

18.13

16.07

13.35

12.91

 

Second quintile

16.05

15.34

15.11

14.27

 

Third quintile

14.95

15.36

14.57

15.53

 

Forth quintile

13.90

14.57

15.87

16.27

 

Most deprived quintile

12.54

13.14

17.70

16.49

 

Expanded CHARLSON INDEX SCORE

Non comorbidity

64.57

68.31

54.05

51.05

< 0.001

Low

29.38

26.47

34.88

37.08

 

High

6.05

5.21

11.08

11.87

 

Opht/ neur complications

 

0.07

0.27

10.33

13.53

< 0.001

Hypertensive heart disease

 

0.00

2.71

0.00

3.16

< 0.001

Other specified kidney diseases

 

3.43

2.28

2.32

2.09

< 0.001

Autoimmune Disease with CKD risk

0.59

0.34

0.38

0.20

< 0.001

Smoking status

Non smoker

66.20

72.30

53.90

65.28

< 0.001

Smoker

17.10

11.37

23.47

13.54

 

Former smoker

16.70

16.34

22.63

21.18

 

Obesity

Underweight

1.53

0.42

0.63

0.16

< 0.001

Normal

31.64

17.78

20.22

11.85

 

Overweight

43.64

43.31

43.21

38.72

 

Class 1 obesity

17.96

27.41

25.16

31.29

 

Class 2/3 obesity

5.23

11.08

10.78

17.98

 

Heart Failure

 

4.60

6.02

6.42

7.83

< 0.001

Atrial Fibrillation

 

6.97

9.83

8.10

10.49

< 0.001

Hypercholesterolemia

 

44.20

43.29

29.23

27.36

< 0.001

Systolic blood pressure

≥ 140 mm Hg

14.93

37.03

16.78

42.95

< 0.001

Diastolic blood pressure

≥ 90 mm Hg

4.83

9.81

4.06

9.74

< 0.001

Anemia

 

17.10

18.04

20.66

24.29

< 0.001

Statins

 

30.91

41.49

49.50

59.70

< 0.001

Platelet / Anticoagulant

 

22.64

32.40

38.54

51.57

< 0.001

Angiotensin-converting enzyme inh.

 

12.63

57.18

23.42

63.59

< 0.001

Angiotensin II receptor antagonists

 

7.09

36.01

11.84

43.37

< 0.001

Aldosterone antagonists

 

4.21

4.06

6.82

5.89

< 0.001