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Table 2 Time span from T2D and/or HTN diagnosis to renal disease evidence and renal function parameters at baseline in the KIDNEES cohort free of Atherosclerotic Cardiovascular Disease (n = 398,477)

From: Cardiovascular events and mortality in chronic kidney disease in primary care patients with previous type 2 diabetes and/or hypertension. A population-based epidemiological study (KIDNEES)

 

CKD without HTN/T2D

CKD with HTN

CKD with T2D

CKD with HTN/T2D

p value

Time Span from T2D and/or HTN diagnosis (years of evolution)

     

T2D

-

-

4.38 [1.89, 8.14]

5.90

[2.94, 9.74]

< 0.001

HTN

-

5.62 [2.32, 9.87]

-

6.77

[3.18, 11.03]

< 0.001

T2D and HTN

-

5.62 [2.32, 9.87]

4.38 [1.89, 8.14]

4.31

[1.72, 7.82]

< 0.001

T2D < 5 years (%)

-

 

54.8

43.1

 

HTN < 5 years (%)

 

45.7

 

38.0

 

T2D < 10 years (%)

-

 

83.7

76.3

 

HTN < 10 years (%)

-

75.6

 

69.7

 

Renal function parameters (pooled imputed data)

     

eGFR severity (mL/min/1.63m2)

    

< 0.001

< 15

0.56

0.34

0.33

0.25

 

15–29

2.15

2.69

2.02

2.19

 

30–44

10.69

16.07

8.82

12.40

 

45–59

65.69

63.01

37.63

46.47

 

60–89

11.33

11.86

22.45

23.75

 

≥ 90

9.58

6.03

28.76

14.94

 

Albuminuria severity (%)

    

< 0.001

normal to mildly increased 1

72.98

70.04

39.11

48.09

 

moderately increased 2

23.37

26.87

54.99

45.52

 

severely increased 3

3.65

3.10

5.90

6.38

 
  1. 1 Albumin to creatinine ratio (ACR) < 30 mg/g or albumin < 20 mg/L; 2 moderately increased: ACR 30–300 mg/g or albumin 20–200 mg/L; 3 severely increased: ACR > 300 mg/g or albumin > 200 mg/L
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BMC Nephrology

ISSN: 1471-2369

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