Incidence and predictors of acute kidney injury among women with severe pre-eclampsia at Mbarara Regional Referral Hospital

Table 2 Predictors of acute kidney injury by logistic regression

Characteristic	Bivariate analysis	p-value	Multivariate analysis	P-value
Characteristic	cOR (95%CI)		aOR (95%CI)
Age (years) 18–25 26–35 > 36	1 0.99(0.36–2.73) 0.52(0.11–2.39)	0.979 0.402
ANC attendance
No	Ref		Ref
Yes	0.14 (0.027,0.73)	0.020	0.03 (0.0007,1.41)	0.075
Eclampsia
No	Ref		Ref
Yes	3.5 (1.04, 11.7)	0.042	5.89 (1.51, 38.88)	0.014
HIV status
Negative	Ref		Ref
Positive	2.18 (0.33, 14.09)	0.410	3.06 (0.28, 32.56)	0.35
SBP > 160 or DBP > 110
No	Ref		Ref
Yes	1.27 (0.58,5.62)	0.312	7.89 (0.81,76.5)	0.074
Gravidity
2 or less	Ref
3 or more	1.72 (0.65, 4.54)	0.268	2.32 (0.26,20.4)	0.44
Parity
2 or less	Ref
3 or more	1.71 (0.65, 4.46)	0.269	0.86 (0.96, 7.73)	0.89
Gestational age at delivery
20–28	Ref
28–34	1.4 (0.32,6.10)	0.654
34 or more	0.93(0.25,3.46)	0.918
Proteinuria
No	Ref		Ref
Yes	1.12 (0.40,3.12)	0.824	1.22 (0.28,5.20)	0.783
HELLP syndrome
No	Ref		Ref
Yes	2.31 (0.79, 6.77)	0.125	1.47(0.26, 8.05)	0.656
Previous pre-eclampsia
No	Ref		Ref
Yes	2.73 (0.72, 10.41)	0.139	4.55 (0.58, 35.66)	0.149
Abruptio placenta
No	Ref		Ref
Yes	1.17 (0.35, 3.95)	0.790	0.83 (0.003, 2.22)	0.138

Abbreviations: ANC Antenatal Care, HIV Human Immunodeficiency Virus, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure

ISSN: 1471-2369