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Table 2 The characteristics of development and validation sets

From: A nomogram to predict hyperkalemia in patients with hemodialysis: a retrospective cohort study

Variable

Development set

(n = 256)

Validation set

(n = 145)

P-value

Age, year

62.62 ± 14.71

61.64 ± 13.37

0.510

Blood flow (mm/s)

241.19 ± 34.80

241.97 ± 32.95

0.827

Height(cm)

162.32 ± 8.15

163.03 ± 7.91

0.399

Pre-dialysis weight (kg)

59.59 ± 12.03

59.99 ± 11.58

0.750

Hemoglobin(g/L)

107.79 ± 22.45

109.94 ± 20.52

0.340

Serum sodium(mmol/L)

138.36 ± 3.71

138.15 ± 3.47

0.575

Serum calcium(mmol/L)

2.13 ± 0.36

2.08 ± 0.38

0.223

Albumin(g/L)

36.43 ± 5.97

35.88 ± 5.35

0.353

TC(mmol/L)

4.35 ± 1.26

4.34 ± 1.34

0.913

HDL(mmol/L)

0.97 ± 0.36

0.96 ± 0.34

0.833

Hemodialysis duration (month)

14 (7, 48)

16 (7, 48)

0.871

Number of hemodialysis sessions

145.5 (36.5, 305)

137 (38, 306)

0.838

Ultrafiltration volume(L)

2500 (1800, 3200)

2700 (1882.50, 3300)

0.203

CRP(mg/L)

4.14 (1, 15.34)

3.17 (1.00, 12.20)

0.498

BUN (mmol/L)

18.1 (11.73, 27.05)

18.7 (10.70, 24.85)

0.681

Uric acid(μmol/L)

360 (246.5, 456)

353 (232, 424)

0.402

eGFR(ml/min)

5.90 (4.30, 9.50)

6.4 (4.30, 10.45)

0.761

Glucose(mmol/L)

5.48 (4.59, 7.42)

6.05 (4.90, 8.45)

0.051

Serum creatinine(μmol/L)

668 (452, 876.5)

675 (369.50, 893.50)

0.783

Serum phosphate(mmol/L)

1.5 (1.16, 1.97)

1.44 (1.05, 1.95)

0.381

TG(mmol/L)

1.36 (0.96, 1.91)

1.37 (0.93, 2.11)

0.777

LDL(mmol/L)

2.04 (1.60, 2.58)

1.98 (1.44, 2.57)

0.675

PTH(pg/ml)

239.60 (103.10, 427.98)

212.00 (101.65, 387.05)

0.163

Gender

  

0.617

 Male

151 (59.0%)

90 (62.1%)

 

 Female

105 (41.0%)

55 (37.9%)

 

Primary disease

  

0.235

 Primary nephropathy

115 (44.9%)

51 (35.17%)

 

 Glomerulonephritis

60 (23.44%)

24 (16.55%)

 

 IgA nephropathy

47 (18.36%)

18 (12.41%)

 

 Membranous nephropathy

5 (1.95%)

8 (5.52%)

 

 Interstitial nephritis

3 (1.17%)

1 (0.69%)

 

 Secondary nephropathy

105 (41.01%)

72 (49.66%)

 

 Diabetes nephropathy

50 (19.53%)

30 (20.69%)

 

 Hypertensive nephropathy

55 (21.48%)

42 (28.97%)

 

 Hereditary nephropathy

7 (2.73%)

6 (4.14%)

 

 Unknown etiology

29 (11.33%)

16 (11.03%)

 

Professional

  

0.636

 Farmer

199 (78.0%)

116 (80.0%)

 

 Worker

8 (3.1%)

4 (2.8%)

 

 Clerk

11 (4.3%)

4 (2.8%)

 

 Retirees

18 (7.1%)

8 (5.5%)

 

 Student

1 (0.4%)

0 (0.0%)

 

 Self-employed

13 (5.1%)

6 (4.1%)

 

 Unemployed people

5 (2.0%)

7 (4.8%)

 

Education level

  

0.653

 Primary school diploma

58 (22.7%)

37 (25.5%)

 

 Junior high school diploma

47 (18.4%)

22 (15.2%)

 

 High school diploma

13 (5.1%)

10 (6.9%)

 

 College diploma

9 (3.5%)

8 (5.5%)

 

 Illiteracy

128 (50.2%)

68 (46.9%)

 

Hemodialysis vascular access

  

0.588

 Temporary tube

13 (5.1%)

7 (4.8%)

 

 Long term tube

81 (31.6%)

39 (26.9%)

 

 Fistula

162 (63.3%)

99 (68.3%)

 

Dialysis modalities

  

1.000

 HD

49 (19.1%)

28 (19.3%)

 

 HD + HF

207 (80.9%)

117 (80.7%)

 

Hyperkalemia

  

1.000

 Yes

154 (60.2%)

88 (60.7%)

 

 No

102 (39.8%)

57 (39.3%)

 

Furosemide

  

0.101

 Yes

184 (71.9%)

92 (63.4%)

 

 No

72 (28.1%)

53 (36.6%)

 

ACEI/ARB

  

0.280

 Yes

179 (79.9%)

93 (64.1%)

 

 No

77 (30.1%)

52 (35.9%)

 

Hypertension

  

0.804

 Yes

58 (22.7%)

31 (21.4%)

 

 No

198 (77.3%)

114 (78.6%)

 

Diabetes mellitus

  

0.254

 Yes

161 (62.9%)

82 (56.6%)

 

 No

95 (37.1%)

63 (43.4%)

 
  1. HK hyperkalemia, TG triglyceride, HDL high-density lipoprotein, CRP C-reactive protein, BUN blood urea nitrogen, eGFR estimated Glomerular Filtration Rate, TC total cholesterol, LDL low-density lipoprotein, PTH parathyroid hormone, HD hemodialysis, HF hemofiltration, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker
  2. Categorical variables are presented as n (%). Continuous variables with normal distribution are reported as mean + SD. Continuous variables with abnormal distribution are given as median (IQR)