Table 3 Comparison of echocardiographic findings between the beginning and end of the study
Parameters | Initial findings | End of study | p |
|---|---|---|---|
LVEF (%) [median (IQR)] | 31 (27-34) | 50 (46-52) | 0.002 |
Systolic dysfunction | |||
 Mild, n (%) | 8 (25.8) | 20 (64.5) | <  0.001 |
 Moderate, n (%) | 16 (51.6) | 9 (29.0) | <  0.01 |
 Severe, n (%) | 7 (22.6) | 2 (6.5) | <  0.01 |
Diastolic dysfunction | |||
 Grade I, n (%) | 10 (32.3) | 19 (61.3) | <  0.01 |
 Grade II, n (%) | 21 (67.7) | 12 (38.7) | <  0.01 |
 Grade III, IV, n (%) | 0 (0) | 0 (0) | – |
Right atrial dilatation, n (%) | 24 (77.4) | 11 (35.5) | <  0.001 |
Right ventricular dilatation, n (%) | 26 (83.9) | 12 (38.7) | <  0.001 |
Left atrial dilatation, n (%) | 16 (51.6) | 7 (22.6) | <  0.001 |
Increased left ventricular wall thickness, n (%) | 11 (33.3) | 9 (29.0) | 0.183 |
Septal thickness, cm (mean + SD) | 2.2 + 0.3 | 1.4 + 0.2 | <  0.001 |
PE, n (%) | 9 (29.0) | 4 (12.9) | 0.035 |
sPAP (median + SD) | 40.75 + 10.61 | 23.55 + 9.20 | <  0.001 |
mPAP (median + SD) | 29.66 + 11.35 | 18.24 + 6.75 | <  0.001 |