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Fig. 1 | BMC Nephrology

Fig. 1

From: Ntrk1 promotes mesangial cell proliferation and inflammation in rat glomerulonephritis model by activating the STAT3 and p38/ERK MAPK signaling pathways

Fig. 1

Ntrk1 was overexpressed in glomerulus of MsPGN rat. A PAS staining was performed on kidney tissues to detect the glomerulus injury. Total cells per glomerulus cross-section and mesangial matrix score was assessed. B IHC was conducted on kidney tissues to detect Ki67 positive cells. C Urine protein of MsPGN rat was researched. D Inflammatory factors expression in glomerulus was investigated using qRT-PCR, including IFN-γ, TNF-α and IL-6. E Ntrk1 mRNA expression in glomerulus was investigated by qRT-PCR. F Ntrk1 protein expression in glomerulus was assessed by Western blot. * P < 0.05. ** P < 0.01. ns, the difference is not statistically significant

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