Table 1 Characteristics of patients included in the hepcidin cohort^a

Male sex, n (%)

24 (56)

35 (78)

0,03

Age (years)

62 (± 16)

64 (± 14)

0,59

BMI (kg/m²)

28,0 (± 4,8)

28,8 (± 7,2)

0,53

eGFR (ml/min/1,73m²)

32 (± 13)

30 (± 12)

0,47

CKD stage G3, n (%)

19 (44)

16 (36)

0,47

CKD stage G4, n (%)

24 (56)

29 (64)

-

Cause of CKD

 Diabetes mellitus, n (%)

13 (30)

13 (29)

0,89

 Glomerulonephritis, n (%)

8 (19)

8 (18)

0,92

 PKD, n (%)

5 (12)

1 (2)

0,08

 Nephrosclerosis, n (%)

11 (26)

12 (27)

0,91

 Other, n (%)

6 (14)

11 (24)

0,21

Oral iron, n (%)

9 (21)

4 (9)

0,13

Intravenous iron, n (%)

1 (2)

0 (0)

-

ESA, n (%)

4 (9)

5 (9)

0,8

Hemoglobin (g/L)

129 (± 16)

132 (± 16)

0,49

Hematocrit (%)

39 (± 5)

40 (± 5)

0,37

Erythrocytes (10¹²/L)

4,2 (± 0,53)

4,4 (0,59)

0,33

Ferritin (µg/L)

121 (76–256)

123 (60–237)

0,78

TSAT (%)

27 (± 9)

26 (± 10)

0,60

S-iron (µmol/L)

16 (± 5)

16 (± 5)

0,9

Hepcidin (nmol/L)^b

5,2 (2,8–10)

4,4 (1,4 – 7,3)

0,18

Hepcidin/ferritin ratio^c

43 (23–60)

31 (17–44)

0,02

CRP (mg/L)

2,0 (0,71 – 5,5)

2,4 (1,3 – 5,6)

0,34

IL-6 (ng/L)

1,8 (1,0 – 3,7)

3,0 (1,2 – 4,5)

0,26

25(OH)D (nmol/L)

56 (± 22)

58 (± 22)

0,74

1,25(OH)₂ (pmol/L)

58 (26–90)

53 (34–90)

0,97

Phosphate (mmol/L)

1,2 (± 0,28)

1,2 (± 0,28)

0,46

Calcium (mmol/L)

2,2 (± 0,14)

2,3 (± 0,11)

0,18

FGF-23 (pg/ml)

92 (71 – 163)

130 (68–179)

0,40