Prognostic value of the combination of neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio and platelet-to-lymphocyte ratio on mortality in patients on maintenance hemodialysis

Table 2 Associations between the inflammation score and all-cause and cardiovascular mortality

	Model 1^a		Model 2^b		Model 3^c		Model 4^d
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
All-cause mortality
The inflammation score = 0	Reference		Reference		Reference		Reference
The inflammation score = 1	1.601 (0.537-4.774)	0.398	1.573 (0.523-4.732)	0.420	1.930 (0.604-6.162)	0.267	2.825 (0.707-11.285)	0.142
The inflammation score = 2	2.148 (0.794-5.814)	0.132	2.018 (0.739-5.508)	0.170	2.067 (0.704-6.068)	0.186	3.300 (0.882-12.344)	0.076
The inflammation score = 3	2.781 (1.153-6.708)	0.023	2.640 (1.085-6.425)	0.032	2.969 (1.115-7.909)	0.029	4.562 (1.342-15.504)	0.015
P for trend	0.013		0.020		0.024		0.010
Cardiovascular mortality
The inflammation score = 0	Reference		Reference		Reference		Reference
The inflammation score = 1	0.801 (0.191-3.366)	0.762	0.775 (0.182-3.292)	0.730	1.029 (0.225-4.694)	0.971	2.033 (0.324-12.764)	0.449
The inflammation score = 2	1.629 (0.516-5.140)	0.405	1.580 (0.496-5.038)	0.439	1.655 (0.475-5.769)	0.429	3.178 (0.619-16.302)	0.166
The inflammation score = 3	2.049 (0.759-5.529)	0.157	1.979 (0.724-5.414)	0.184	2.200 (0.708-6.835)	0.173	4.027 (0.882-18.384)	0.072
P for trend	0.076		0.087		0.110		0.047

^aModel 1: unadjusted
^bModel 2: adjusted for age and sex
^cModel 3: adjusted for model 2 covariates and body mass index, primary cause of ESKD, mean arterial pressure, and 24 h urine output
^dModel 4: adjusted for model 3 covariates and hemoglobin, albumin, calcium, phosphorus, iPTH, total cholesterol, and triglyceride
Abbreviations: HR hazard ratio, 95% CI 95% confidence interval

ISSN: 1471-2369