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Table 2 Comparing demographic and laboratory data between COV and COV-HD patients

From: Characterization of regulatory T cells in SARS-CoV-2 infected hemodialysis patients: relation to clinical and radiological severity

 

COV group (n = 30)

COV-HD group (n = 30)

P Value

Demographic and Clinical data

Age

60.6 (13.6)

54 (8.9)

0.115 a

Gender

 Male

9 (30)

21 (70)

0.006

 Female

21 (70)

9 (30)

Diabetes

14 (46.7)

13 (43)

0.5

Number of days of hospital admission

15 (3–33)

3 (0–12)

0.001 a

O2 Saturation at admission

88 (60–99)

89 (72–96)

0.008 a

Place of stay (OPC, Ward, ICU)

 OPC

2 (6.7)

12 (40)

0.009c

 Ward

14 (46.7)

10 (33.5)

 ICU

14 (46.7)

8 (26.5)

Outcome

 OPC

1 (3.3)

11 (36.5)

0.005c

 Discharge

16 (53.3)

12 (40)

 Death

13 (43.3)

7 (23.5%)

Radiological Data

 GGO percentage%

50 (0–86)

45 (0–69)

0.19 a

 Total severity score in CT (TSS) (out of 20)

7.5 (2–15)

7 (2–15)

0.12 a

 TSS (Severe > 7.5)

16 (53%)

10 (33%)

0.08 a

Laboratory data

CBC and Coagulation

 Hemoglobin (mg/dl)

11.25 (6.5–17.6)

9.5 (7.8–12.7)

< 0.001 a

 Total WBCs (cell/ μl)

8616 (3200–20,800)

7300 (3560–22,500)

0.423a

 Neutrophil (cell/ μl)

6790 (2080–14,890)

4346 (2242–18,225)

0.152 a

 Lymphocyte (cell/ μl)

1100 (500–3600)

1204 (480–5000)

0.9 a

 NL ratio

5.6 (1.81–13.22)

2.8 (1.84–21.75)

0.132 a

D-dimer (ng/ml)

 Less than 200

19 (63.3%)

13 (43.3)

0.04 a

 200–500

8 (26.7%)

4 (13.3)

 More than 500

3 (10%)

13 (43.3)

Flowcytometry Data

 CD4+ T cells (cell/ μl)

33.8 (2.2–359.1)

52.16 (1.92–399.6)

0.4 a

 Tregs (cell/ μl)

0.011 (0–0.33)

0.028 (0–5.77)

0.1 a

 CD39 expressing Tregs (cell/ μl)

0.002 (0–0.14)

0.006 (0–5.6)

0.04 a

  1. Non-parametric data: Median (25–75%)
  2. Nominal data: Number (Percentage)
  3. a Mann-Whitney U test
  4. C chi square test